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Utilizing IL-12, IL-15 and IL-7 as Mucosal Vaccine Adjuvants

Liljana Stevceva1, Marcin Moniuszko, Maria Grazia Ferrari

  • 1Partners AIDS Research Center, MGH, Harvard Medical School, CNY Build. 149, Room 5234e, Charlestown, MA 02129, USA.

Letters in Drug Design & Discovery
|May 15, 2007
PubMed

In this paper we review and discuss three of the most exciting and promising cytokines for therapeutic intervention and immunomodulation of immune responses including those on mucosal surfaces. The main properties of IL-12, IL-15 and IL-7 are described and the studies utilizing these cytokines as immunomodulators and vaccine adjuvants discussed.

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