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Updated: Jul 15, 2026

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Published on: October 2, 2020
Low plasma dehydroepiandrosterone sulfate level and its relationship to adiponectin in hemodialysis patients
T Nieszporek1, J Witkowicz, L Nowak
1Department of Nephrology, Endocrinology and Metabolic Diseases, Medical University of Silesia in Katowice, Poland.
Abstract:
The aim of the present study was to assess the relationship between plasma DHEA-S and adiponectin concentrations in hemodialyses patients (HD). Plasma adiponectin, DHEA-S, cholesterol, and albumin levels were estimated in 94 HD and 46 healthy subjects (HS). In HD, a significantly lower plasma DHEA-S concentration (2.5+/-0.2 vs. 4.7+/-0.4 micromol/L respectively; p = 0.002) but significantly higher plasma adiponectin level (15.0+/-0.7 vs. 8.7+/-0.8 microg/mL respectively; p = 0.004) than in HS were found. Only in uremic patients was a significant negative correlation found between plasma adiponectin and DHEA-S concentrations (tau = -0.210; p = 0.001). Decreased plasma DHEA-S level is associated with increased adiponectinemia in uremic patients.
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