Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Ascidian notochord morphogenesis.

Di Jiang1, William C Smith

  • 1Sars International Centre for Marine Molecular Biology, Bergen, Norway.

Developmental Dynamics : an Official Publication of the American Association of Anatomists
|May 15, 2007
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

UHPose-VAD: Unsupervised Video Anomaly Detection via Pose-Graph Learning and Normalizing Flow.

Journal of imaging·2026
Same author

In Science Journals.

Science (New York, N.Y.)·2026
Same author

In Science Journals.

Science (New York, N.Y.)·2026
Same author

In Other Journals.

Science (New York, N.Y.)·2026
Same author

Melatonin Alleviates Graft Biliary Fibrosis by Inhibiting VIM<sup>+</sup> Cholangiocyte Subcluster via Hypoxia/TGF-β-CREM-VIM Axis.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2026
Same author

In Science Journals.

Science (New York, N.Y.)·2026
Same journal

Multi-stage transcriptome analysis reveals genetic orchestration of rat testis development.

Developmental dynamics : an official publication of the American Association of Anatomists·2026
Same journal

Three-dimensional observation of the muscle-tendon integration process in mouse embryos.

Developmental dynamics : an official publication of the American Association of Anatomists·2026
Same journal

Goofy/123Cre lineage tracing differentiates olfactory and vomeronasal neurons from GnRH-1 and terminal nerve neurons during neuronal migration and reveals additional olfactory placode-derived cells in the brain.

Developmental dynamics : an official publication of the American Association of Anatomists·2026
Same journal

Prenatal sexual dimorphism in human pelvic tilt at the onset of fetal ossification.

Developmental dynamics : an official publication of the American Association of Anatomists·2026
Same journal

Meet the editorial team. An interview with Ralph Marcucio, Assistant Editor, University of California San Francisco, United States.

Developmental dynamics : an official publication of the American Association of Anatomists·2026
Same journal

Editorial highlights.

Developmental dynamics : an official publication of the American Association of Anatomists·2026
See all related articles

Ascidian notochord development, a simple model for chordate morphogenesis, involves cell shape changes and rearrangement. This process forms a hydrostatic skeleton essential for larval locomotion.

Area of Science:

  • Developmental biology
  • Cellular morphogenesis
  • Chordate embryology

Background:

  • The notochord is a key structure in chordate development, providing skeletal support.
  • Ascidians offer a simplified model system for studying notochord morphogenesis due to their small cell numbers (approx. 40 cells).
  • Understanding notochord development sheds light on fundamental cellular behaviors.

Purpose of the Study:

  • To describe the cellular behaviors during ascidian notochord morphogenesis.
  • To highlight the ascidian as an experimental model for studying chordate notochord development.
  • To explore variations in notochord lumen formation among ascidian species.

Main Methods:

  • Observation of cellular behaviors during ascidian embryogenesis.

Related Experiment Videos

  • Comparative analysis of notochord development across different ascidian species.
  • Focus on cell shape changes, rearrangement, polarity, and extracellular environment alterations.

    • Main Results:

    • Ascidian notochord development involves epithelial-to-rod conversion and two phases of elongation.
    • Convergent extension drives initial cell intercalation and elongation.
    • Notochord volume increase occurs via extracellular pockets forming a lumen in some species, but not others.
    • The final notochord functions as a hydrostatic skeleton for larval locomotion.

    Conclusions:

    • Ascidian notochord morphogenesis exemplifies fundamental cell behaviors like shape change and rearrangement.
    • The ascidian model simplifies the study of complex chordate developmental processes.
    • Variations in lumen formation highlight diverse strategies within ascidian notochord development.