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Simulation of GABA function in the basal ganglia: computational models of GABAergic mechanisms in basal ganglia

Jeffery R Wickens1, Gordon W Arbuthnott, Tomomi Shindou

  • 1Basal Ganglia Research Group, School of Medical Sciences, University of Otago, Dunedin, New Zealand. jeff.wickens@stonebow.otago.ac.nz

Progress in Brain Research
|May 15, 2007
PubMed

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γ-aminobutyric acid or GABA, plays a pivotal role as an inhibitory neurotransmitter in the brain. GABA pathway potentiators, also known as GABAergic drugs, are a class of pharmaceutical agents designed to enhance the functioning of the GABAergic system. These medications primarily treat epilepsy, a neurological disorder characterized by recurrent seizures.
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