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Related Experiment Video

Updated: Jul 15, 2026

A Mouse Model to Evaluate the Long-Term Structural and Functional Outcomes after the Reversal of Prolonged Unilateral Ureteric Obstruction

A Mouse Model to Evaluate the Long-Term Structural and Functional Outcomes after the Reversal of Prolonged Unilateral Ureteric Obstruction

Published on: July 18, 2025

Malignant ureteral obstruction: outcomes after intervention. Have things changed?

Lih-Ming Wong¹, Laurence K Cleeve, Alvin D Milner

¹Division of Surgical Oncology, Urology, Peter MacCallum Cancer Centre, East Melbourne, Australia.

The Journal of Urology

|May 15, 2007

Summary

Malignant ureteral obstruction decompression offers poor survival, with metastases and prior malignancy treatment being key negative prognostic factors. Complications remain high despite improved technical success.

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Last Updated: Jul 15, 2026

A Mouse Model to Evaluate the Long-Term Structural and Functional Outcomes after the Reversal of Prolonged Unilateral Ureteric Obstruction

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Published on: July 18, 2025

An Immature Murine Model of Reversible Unilateral Ureteral Obstruction

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Published on: April 4, 2025

Technical Modification of the Terminal Ureter During Total Transperitoneal Laparoscopic Nephroureterectomy for Upper Urinary Tract Urothelial Carcinoma

Technical Modification of the Terminal Ureter During Total Transperitoneal Laparoscopic Nephroureterectomy for Upper Urinary Tract Urothelial Carcinoma

Published on: November 22, 2019

Area of Science:

Urology
Oncology
Nephrology

Background:

Malignant ureteral obstruction significantly impacts patient outcomes.
Effective decompression strategies are crucial for managing this condition.

Purpose of the Study:

To analyze clinical outcomes of malignant ureteral obstruction decompression.
Identify prognostic factors, technical success, complication rates, and hospitalization duration.

Main Methods:

Retrospective analysis of 102 patients undergoing decompression for malignant ureteral obstruction (1991-2003).
Examined overall survival, prognostic factors, technical failure, complications, and hospitalization.

Main Results:

Median overall survival was 6.8 months; 12-month survival was 29%.
Metastases and prior malignancy treatment were associated with inferior survival.
Decompression technical success was 94%, but complication rates reached 53%.

Conclusions:

Overall survival for malignant ureteral obstruction remains poor.
Prognostic factors for decreased survival and prolonged hospitalization were identified.
While technical success has improved, complication rates post-decompression are still high.