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Related Concept Videos

Reticular Dermis01:15

Reticular Dermis

The papillary and reticular dermis are the two layers of the dermis. They are made of connective tissue with fibers of collagen extending from one to the other, making the border between the two somewhat indistinct. The dermal papillae extending into the epidermis belong to the papillary layer, whereas the dense collagen fiber bundles below belong to the reticular layer.
Reticular Layer
Underlying the papillary layer is the much thicker reticular layer, composed of dense, irregular connective...
Papillary Dermis01:11

Papillary Dermis

Dermis
The dermis might be considered the "core" of the integumentary system, as distinct from the epidermis and hypodermis. It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands. The dermis is made of two layers of connective tissue that comprise an interconnected mesh of elastin and collagenous fibers, produced by fibroblasts.
Papillary Layer
The papillary layer is made of loose, areolar connective tissue, which means the collagen and...
Confocal Fluorescence Microscopy01:16

Confocal Fluorescence Microscopy

Confocal microscopy is an advanced microscopic technique. The prime advantage of the confocal microscope over other microscopy techniques is its ability to block the out-of-focus light from the illuminated samples using pinholes. It is widely used with fluorescence optics to obtain high-resolution, sharp contrast images. Unlike optical microscopes, confocal microscopes use a focused beam of light laser to scan the entire sample surface at different z-planes. These microscopes are, therefore,...
Skin Diseases and Disorders01:23

Skin Diseases and Disorders

Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Factors Affecting Drug Response: Overview01:21

Factors Affecting Drug Response: Overview

When it comes to infants and young children, they are typically administered smaller doses of medication in comparison to adults. This is primarily because their organ functions still need to fully develop, meaning their bodies are not as efficient at metabolizing or eliminating drugs. Additionally, their blood-brain barrier is more permeable than in adults. As a result, high concentrations of drugs can easily penetrate the central nervous system (CNS), potentially leading to neurological...
Factors Affecting Dissolution: Drug pKa, Lipophilicity and GI pH01:21

Factors Affecting Dissolution: Drug pKa, Lipophilicity and GI pH

Drug absorption within the gastrointestinal (GI) tract is a complex process influenced by several critical factors, including the site pH, the drug's dissociation constant (pKa), and the drug's lipophilicity. The GI tract exhibits a pH gradient, with an acidic environment in the stomach and a more alkaline environment in the small intestine. This pH variation directly affects the ionization state of drugs.
A drug's pKa and the pH of the gastrointestinal (GI) tract play crucial roles in drug...

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Related Experiment Video

Updated: Jul 15, 2026

Comparing Bibliometric Analysis Using PubMed, Scopus, and Web of Science Databases
05:02

Comparing Bibliometric Analysis Using PubMed, Scopus, and Web of Science Databases

Published on: October 24, 2019

Refining dermatology journal impact factors using PageRank.

Robert P Dellavalle1, Lisa M Schilling, Marko A Rodriguez

  • 1Department of Veterans Affairs Medical Center, Denver, USA. robert.dellavalle@uchsc.edu

Journal of the American Academy of Dermatology
|May 15, 2007
PubMed
Summary

Adjusting journal impact factor by citation origin refines dermatology journal rankings. This method better reflects journal prestige by weighting citations from more influential sources, offering a more accurate status measure.

Related Experiment Videos

Last Updated: Jul 15, 2026

Comparing Bibliometric Analysis Using PubMed, Scopus, and Web of Science Databases
05:02

Comparing Bibliometric Analysis Using PubMed, Scopus, and Web of Science Databases

Published on: October 24, 2019

Area of Science:

  • Dermatology
  • Bibliometrics
  • Journal Impact Factor Analysis

Background:

  • The standard journal impact factor relies on raw citation counts, neglecting the prestige of citing journals.
  • This study investigates the impact of citation origin on dermatology journal rankings.

Purpose of the Study:

  • To re-evaluate dermatology journal status by incorporating citation origin into impact factor calculations.
  • To assess how adjusting for citation origin alters the perceived impact and ranking of dermatology journals.

Main Methods:

  • A weighted PageRank algorithm was applied to 2003 impact factors of dermatology journals.
  • Citations from more frequently cited journals were given greater weight.

Main Results:

  • Journal rankings shifted, with some journals like Contact Dermatitis and Burns significantly improving their positions.
  • The Journal of the American Academy of Dermatology advanced in rank, while others like Seminars in Cutaneous Medicine and Surgery declined.
  • The Journal of Investigative Dermatology's top ranking remained unaffected by this adjustment.

Conclusions:

  • Adjusting for citation origin offers a more nuanced and accurate measure of dermatology journal status.
  • Current impact factor metrics do not account for citation source quality, potentially misrepresenting journal influence.
  • Future measures could benefit from incorporating expert opinion, such as surveys of dermatologists' journal esteem.