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The role of preventive cardiology in systemic lupus erythematosus
Jennifer Rae Elliott1, Susan Manzi, Daniel Edmundowicz
1University of Pittsburgh School of Medicine, S727 Biomedical Sciences Tower, 3500 Terrace Street, Pittsburgh, PA 15261, USA. elliottjr@upmc.edu
Insights
Systemic lupus erythematosus (SLE) patients face increased cardiovascular disease risk. Integrating preventive cardiology into SLE care is crucial for managing this leading cause of death.
Area of Science:
- Rheumatology
- Cardiology
- Public Health
Background:
- Cardiovascular disease (CVD) is a primary cause of mortality in systemic lupus erythematosus (SLE) patients.
- Accelerated atherosclerosis in SLE is linked to traditional CVD risk factors, inflammation, and lupus-specific factors.
- Current evaluation of CVD risk in SLE patients is insufficient despite known risks.
Purpose of the Study:
- To highlight the significant cardiovascular risk in SLE patients.
- To advocate for the integration of preventive cardiology into multidisciplinary SLE care.
- To emphasize the need for expert cardiovascular risk assessment in SLE management.
Main Methods:
- Review of current understanding of CVD in SLE.
- Analysis of the interplay between traditional risk factors, inflammation, and SLE.
- Proposal for enhanced patient care protocols.
Main Results:
- Cardiovascular disease is a leading cause of death in SLE patients.
- Premature atherosclerosis is a significant concern in this population.
- Sub-optimal assessment of traditional cardiovascular risk factors exists.
Conclusions:
- Preventive cardiologists should be integral to SLE patient care.
- Enhanced cardiovascular risk evaluation is necessary for SLE patients.
- Multidisciplinary care including preventive cardiology can improve outcomes for SLE patients.
Abstract:
With improved therapeutic advances in the care of systemic lupus erythematosus patients, cardiovascular disease has emerged as a leading cause of death. Premature atherosclerosis in lupus patients is probably an interaction between traditional cardiovascular risk factors, inflammatory factors, and factors related to lupus itself. Despite knowledge of this accelerated cardiac risk, evaluation of traditional risk factors has been sub-par. We propose that lupus patients be evaluated by preventive cardiologists and have access to their expertise and resources. In addition to nephrologists and dermatologists, preventive cardiologists should be an integral part of the care of patients with lupus.
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