A new episodic ataxia syndrome with linkage to chromosome 19q13
Kevin A Kerber1, Joanna C Jen, Hane Lee
1Department of Neurology, UCLA, Los Angeles, California 90095-1769, USA.
Background:
Multiple episodic ataxia phenotypes and genotypes have been described.
Objective:
To describe a new episodic ataxia syndrome.
Design:
Genomewide linkage analysis with dense single nucleotide polymorphism arrays.
Setting:
University clinic. Patients Family with lifelong episodes of ataxia and normal interictal examination results.
Results:
Suggestive linkage (logarithm of odds score, 3.27) to a 10-centimorgan region on chromosome 19q13.
Conclusion:
A new dominantly inherited episodic ataxia syndrome is linked to chromosome 19q.
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