Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Glaucoma: Overview01:25

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Increased Intracranial Pressure l: Introduction01:14

Increased Intracranial Pressure l: Introduction

Intracranial hypertension is a sustained elevation of intracranial pressure (ICP) above 22 mm Hg. In supine adults, normal ICP is ~7–15 mm Hg.The rigid, nonexpandable cranium contains three components—brain tissue, blood, and cerebrospinal fluid (CSF)—that total ~1,700 mL in a typical adult: 1,400 mL brain (~80%), 150 mL blood (~10%), and 150 mL CSF (~10%). According to the Monro–Kellie doctrine, total intracranial volume is effectively fixed. When one component expands, CSF and venous blood...
Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Letter to the Editor: The effects of breaks on digital eye strain, dry eye and binocular vision: Testing the 20-20-20 rule.

Contact lens & anterior eye : the journal of the British Contact Lens Association·2023
Same author

Risk associated with treatments for meibomian gland dysfunction.

Contact lens & anterior eye : the journal of the British Contact Lens Association·2023
Same author

Morphological retinal changes in keratoconus.

The ocular surface·2022
Same author

Transdermal anti-inflammatory therapy for aqueous deficiency.

Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists)·2021
Same author

Could contact lens dryness discomfort symptoms sometimes have a neuropathic basis?

Eye and vision (London, England)·2021
Same author

Why the symptoms and objective signs of dry eye disease may not correlate.

Journal of optometry·2020

Related Experiment Video

Updated: Jul 14, 2026

Trabecular Meshwork Response to Pressure Elevation in the Living Human Eye
09:03

Trabecular Meshwork Response to Pressure Elevation in the Living Human Eye

Published on: June 20, 2015

Experimentally increased intraocular pressure using digital forces.

Charles W McMonnies1, Gavin C Boneham

  • 1School of Optometry and Vision Science, University of New South Wales, Kensington, Australia. c.mcmonnies@unsw.edu.au

Eye & Contact Lens
|May 16, 2007
PubMed
Summary

This study shows that applying digital force to the eye reliably increases intraocular pressure (IOP), enabling videokeratography at higher IOP levels. This method allows for a wider range of IOP examination in vivo.

More Related Videos

Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents
10:10

Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents

Published on: February 15, 2022

Translaminar Autonomous System Model for the Modulation of Intraocular and Intracranial Pressure in Human Donor Posterior Segments
08:55

Translaminar Autonomous System Model for the Modulation of Intraocular and Intracranial Pressure in Human Donor Posterior Segments

Published on: April 24, 2020

Related Experiment Videos

Last Updated: Jul 14, 2026

Trabecular Meshwork Response to Pressure Elevation in the Living Human Eye
09:03

Trabecular Meshwork Response to Pressure Elevation in the Living Human Eye

Published on: June 20, 2015

Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents
10:10

Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents

Published on: February 15, 2022

Translaminar Autonomous System Model for the Modulation of Intraocular and Intracranial Pressure in Human Donor Posterior Segments
08:55

Translaminar Autonomous System Model for the Modulation of Intraocular and Intracranial Pressure in Human Donor Posterior Segments

Published on: April 24, 2020

Area of Science:

  • Ophthalmology
  • Biomedical Engineering
  • Corneal Imaging

Background:

  • Intraocular pressure (IOP) is a critical factor in eye health.
  • Videokeratography is a key diagnostic tool for assessing corneal topography.
  • Current methods for manipulating IOP during videokeratography are limited.

Purpose of the Study:

  • To evaluate the reliability of a novel digital force method for increasing IOP.
  • To determine if this method can be used during videokeratography.
  • To assess the influence of induced IOP increments on anterior corneal curvature.

Main Methods:

  • Digital force (light and firm) applied to the temporal sclera.
  • Intraocular pressure (IOP) measured using noncontact tonometry.
  • Measurements taken with and without real-time IOP feedback to simulate videokeratography conditions.

Main Results:

  • Digital force reliably increased IOP in a dose-dependent manner.
  • Mean IOP increments ranged from +40% to +345% depending on force level and subject.
  • Induced IOP increments were consistent, with without-result-feedback values falling within 95% confidence limits.

Conclusions:

  • Digital force application is a reliable method for increasing IOP.
  • This technique allows for videokeratography at higher and wider IOP ranges.
  • The method facilitates examination of IOP's influence on corneal surface curvature in vivo.