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Oral C-4 plastic explosive in humans - a case series
James O J Davies1, Darren M Roberts, Ariyasena Hittarage
1South Asian Clinical Toxicology Research Collaboration Clinical Unit, Anuradhapura General Hospital, North Central Province, Sri Lanka.
Clinical Toxicology (Philadelphia, Pa.)
|May 16, 2007
Summary
Oral C-4 plastic explosive poisoning can cause severe symptoms like seizures and metabolic disturbances. Prompt medical care, including benzodiazepines for seizures, is crucial for survival and recovery.
Area of Science:
- Toxicology
- Emergency Medicine
- Clinical Case Series
Background:
- C-4 plastic explosive is widely used in military and civilian demolition.
- Severe toxicity from C-4 ingestion is rare but documented.
- Oral C-4 exposure can lead to significant adverse health effects.
Observation:
- A cohort of 17 healthy male soldiers with oral C-4 poisoning was studied.
- Patients presented with seizures, headache, nausea, and vomiting.
- Laboratory findings included hypokalemia and elevated muscle/liver enzymes.
Findings:
- All 17 patients survived C-4 poisoning.
- Seizures were a prominent clinical feature.
- Metabolic acidosis was observed in two patients post-seizure, resolving spontaneously.
Implications:
- C-4 poisoning should be considered in patients with seizures and potential exposure.
- Standard resuscitation and supportive care are essential.
- Benzodiazepines are recommended for managing C-4-induced seizures and agitation.
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