Related Experiment Video
Updated: Jun 12, 2026
Development of an In Vitro Ocular Platform to Test Contact Lenses
Published on: April 6, 2016
In vitro water wettability of silicone hydrogel contact lenses determined using the sessile drop and captive bubble
Carole Maldonado-Codina1, Philip B Morgan
1Eurolens Research, Faculty of Life Sciences, The University of Manchester, Manchester, United Kingdom. c.m-codina@manchester.ac.uk
Abstract:
This study investigated the water contact angles of five commercially available silicone hydrogel contact lenses (Acuvue Advance, Acuvue Oasys, Focus Night & Day, O2 Optix, and PureVision) using sessile drop and captive bubble techniques. The only lens type that showed a significant difference in water contact angle when measured by sessile drop direct from the blister compared with after 48 h of soaking/washing in saline was the Acuvue Advance lens (from 66 degrees to 96 degrees, respectively) (p=0.0002), presumably because of surface active agents within the blister solution. The water contact angle data split the lenses into two distinct groups (p
