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Atherosclerosis I: Introduction

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Updated: Jul 14, 2026

A Mouse Model for Pathogen-induced Chronic Inflammation at Local and Systemic Sites

A Mouse Model for Pathogen-induced Chronic Inflammation at Local and Systemic Sites

Published on: August 8, 2014

[Infection and atherosclerosis].

P Syrovátka¹, P Kraml

¹Klinika kardiologie IKEM Praha. petr.syrovatka@seznam.cz

Vnitrni Lekarstvi

|May 17, 2007

Summary

Atherosclerosis, a chronic inflammatory disease and leading cause of cardiovascular death, may be linked to infectious agents. Research explores the role of infections in atherosclerosis development and potential interventions.

Area of Science:

Cardiovascular Science
Immunology
Infectious Diseases

Context:

Atherosclerosis is a primary cause of global mortality, predominantly from cardiovascular diseases.
Traditional risk factors do not explain all atherosclerosis cases, prompting investigation into environmental influences.
Infectious agents are increasingly recognized as potential contributors to atherosclerosis.

Purpose:

To provide an overview of the role of infectious agents in atherosclerosis.
To discuss the interactions between infection and atherogenic processes.
To explore potential intervention strategies targeting infectious causes of atherosclerosis.

Summary:

Atherosclerosis, a chronic inflammatory condition, is the leading cause of death worldwide and in developing nations.

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A Human Ex Vivo Atherosclerotic Plaque Model to Study Lesion Biology

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Published on: May 6, 2014

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Last Updated: Jul 14, 2026

A Mouse Model for Pathogen-induced Chronic Inflammation at Local and Systemic Sites

A Mouse Model for Pathogen-induced Chronic Inflammation at Local and Systemic Sites

Published on: August 8, 2014

A Human Ex Vivo Atherosclerotic Plaque Model to Study Lesion Biology

A Human Ex Vivo Atherosclerotic Plaque Model to Study Lesion Biology

Published on: May 6, 2014

Infectious agents are being investigated for their role in atherosclerosis, particularly when traditional risk factors are absent.

Studies indicate that infections can promote atherogenic processes and interact with established risk factors.

Impact:

Highlights the significance of infectious agents in atherosclerosis etiology and pathogenesis.
Suggests new avenues for understanding and managing cardiovascular diseases.
Informs the development of novel intervention strategies for atherosclerosis.