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Updated: Jul 14, 2026

An In Vivo Estrogen Deficiency Mouse Model for Screening Exogenous Estrogen Treatments of Cardiovascular Dysfunction After Menopause
Published on: August 13, 2019
[Androgen deficiency in women: indication and risks of testosterone or DHEA treatment]
1martindupan@bluewin.ch
Abstract:
Androgen deficiency syndrome is defined by impaired well being and libido in women with adequate estrogenization and low levels of total serum testosterone (T). The causes of low T levels are discussed. Seven placebo controlled studies have shown that percutaneous administration of T is able to increase sexual activity and libido in ovariectomized women (5 studies), after hypophysectomy and in natural menopause. DHEA (50 mg/d) is beneficial only in women with Addison disease or after hypophysectomy but not in natural adrenopause. Other beneficial and side effects of androgenotherapy are discussed in particular the breast cancer risk.
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