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Does tenofovir influence efavirenz pharmacokinetics?

Margalida Rotger1, Sara Colombo, Hansjakob Furrer

  • 1Institute of Microbiology, University Hospital, Lausanne, Switzerland.

Antiviral Therapy
|May 17, 2007
PubMed
Summary

A study found no clear pharmacokinetic interaction between tenofovir (TFV) and efavirenz (EFV). However, slow efavirenz metabolizers taking TFV showed higher drug levels, suggesting a potential interaction in this subgroup.

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