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Updated: Jul 14, 2026

A Murine Model of Group B Streptococcus Vaginal Colonization
Published on: November 16, 2016
Group B streptococcal cellulitis in infancy
Manoj K Mittal1, Samir S Shah, Eron Y Friedlaender
1Division of Emergency Medicine, The Children's Hospital of Philadelphia, Philadelphia, PA 19104-4399, USA. manojmital@yahoo.com
Insights
Group B Streptococcus (GBS) causes infant cellulitis, often linked to bacteremia. Prompt septic workup, including blood and CSF cultures, is crucial for early diagnosis and treatment in infants under 3 months.
Area of Science:
- Pediatrics
- Infectious Diseases
- Neonatology
Background:
- Cellulitis in infants under 3 months is frequently caused by Group B Streptococcus (GBS).
- GBS cellulitis in this age group can be associated with serious systemic infections like bacteremia.
Observation:
- A case of a 6-week-old infant presenting with both cellulitis and meningitis is detailed.
- This case highlights the potential complexity and diagnostic challenges of GBS infections in neonates.
Findings:
- The study emphasizes the necessity of a comprehensive septic workup, including blood and cerebrospinal fluid (CSF) cultures, for infants with cellulitis.
- It also reviews GBS cellulitis and meningitis, noting cases with initially normal CSF analysis.
Implications:
- Early and thorough diagnostic evaluation is critical for managing GBS infections in young infants.
- Understanding the association between cellulitis and potential systemic involvement like meningitis guides clinical practice and improves patient outcomes.
Abstract:
Cellulitis in an infant younger than 3 months is most commonly caused by group B streptococci (GBS). A baby with cellulitis in this age group should have a full septic workup including blood and cerebrospinal fluid cultures, as GBS cellulitis may be associated with bacteremia. We discuss a 6-week-old baby with cellulitis and meningitis to illustrate the potential complexity of this infectious disease process. We also present a concise review of GBS cellulitis and of meningitis with initially normal cerebrospinal fluid analysis.
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