Related Experiment Video
Updated: Jul 14, 2026

Development of Compendium for Esophageal Squamous Cell Carcinoma
Published on: April 12, 2024
Carcinoma arising from an epiphrenic diverticulum: a frequently misdiagnosed disease
1Division of Thoracic Surgery, Department of Surgery, Taichung Veterans General Hospital, Taichung, Taiwan.
Abstract:
Epiphrenic diverticulum is rare, comprising of about 10% of all esophageal diverticula. Carcinoma arising within such a diverticulum is even less common. We report on two patients with squamous cell carcinoma arising from an epiphrenic diverticulum. Some features of malignant change related to the epiphrenic diverticula were misdiagnosed or missed in our cases and other reports due to lack of clinical experience. It is important to exclude the possibility of malignancy as this is vital for surgical planning. Although the prognosis for patients with malignancy arising from an epiphrenic diverticulum is generally poor, a high index of suspicion may increase the chance of cure.
Related Concept Videos
Diverticular Disease of the Colon
Cellular Adaptation IV: Dysplasia and Metaplasia
Barrett Esophagus-I: Introduction
This constant acid exposure transforms the esophagus's pink mucosal lining (stratified squamous epithelium) into a type of lining more similar...
Appendicitis
Barrett Esophagus-II: Clinical Manifestations and Management
To diagnose Barrett's esophagus, healthcare providers often recommend an endoscopy for those showing symptoms of acid reflux. The procedure entails...
Appendicitis-I: Introduction
Etiology: Appendicitis can arise from various causes, primarily rooted in the obstruction of the appendix lumen. Factors contributing to this obstruction include fecal accumulation, lymphoid hyperplasia and, in...