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Related Concept Videos

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The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
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Related Experiment Video

Updated: Jul 14, 2026

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery
09:53

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery

Published on: July 5, 2021

Supratentorial primitive neuroectodermal tumor during pregnancy. Case report.

S Ulivieri1, G Oliveri, F Filosomi

  • 1Department of Neurosurgery, Santa Maria alle Scotte Hospital, 53100 Siena, Italy. simone.ulivieri@tiscali.it

Minerva Ginecologica
|May 17, 2007
PubMed
Summary

A pregnant woman with a primitive neuroectodermal tumor (PNET) underwent successful surgical removal. However, tumor recurrence necessitated further treatment, including chemotherapy and radiotherapy after delivery.

Related Experiment Videos

Last Updated: Jul 14, 2026

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery
09:53

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery

Published on: July 5, 2021

Area of Science:

  • Neuro-oncology
  • Obstetrics and Gynecology

Background:

  • Pregnancy presents unique challenges for managing central nervous system tumors.
  • Primitive neuroectodermal tumors (PNETs) are rare and aggressive brain tumors.

Observation:

  • An 18-year-old primipara in her second trimester presented with symptoms of increased intracranial pressure, including headache, diplopia, and left hemiparesis.
  • A supratentorial mass was diagnosed, and surgical resection was performed at 20 weeks gestation.

Findings:

  • Immunohistochemical analysis confirmed the tumor as a primitive neuroectodermal tumor (PNET).
  • Post-discharge, the patient experienced recurrent symptoms and radiological evidence of a temporal lesion, indicating tumor recurrence.
  • A second surgical resection was performed post-caesarean delivery, followed by combined chemotherapy and radiotherapy.

Implications:

  • This case highlights the importance of vigilant monitoring for pregnant patients with brain tumors.
  • Multimodal treatment strategies, including surgery, chemotherapy, and radiotherapy, may be necessary for managing recurrent PNETs during pregnancy.
  • Successful management requires a multidisciplinary approach involving neurosurgery, oncology, and obstetrics.