Related Experiment Video
Updated: Jul 14, 2026
06:33
3-D Imaging and Analysis of Neurons Infected In Vivo with Toxoplasma gondii
Published on: December 9, 2014
Congenital toxoplasmosis in dizygotic twins, Paraná, Brazil
Dina Lúcia Morais Falavigna1, Eduardo Vinicius Roncada, Deise Nakazora
1Programa de Pós-graduação em Análises Clínicas, Universidade Estadual de MaringáPR, Brasil.
Insights
This study reports the first case of congenital toxoplasmosis in dizygotic twins in Brazil. Early maternal diagnosis and lifelong child follow-up are crucial to prevent long-term damage from this infection.
Area of Science:
- * Infectious Diseases
- * Maternal-Fetal Medicine
- * Parasitology
Background:
- * Congenital toxoplasmosis poses significant risks to newborns.
- * Toxoplasma gondii infection during pregnancy requires careful management.
- * Dizygotic twinning presents unique considerations for prenatal care.
Observation:
- * The first documented case of congenital toxoplasmosis in dizygotic twins in Brazil.
- * Detailed clinical observations of the affected twin pair.
- * Evaluation of diagnostic and management strategies in the Brazilian context.
Findings:
- * Confirmation of congenital toxoplasmosis transmission in a dizygotic twin pregnancy.
- * Highlighting the challenges in diagnosing maternal and congenital infections.
- * Demonstrating the potential for severe developmental outcomes without timely intervention.
Implications:
- * Emphasizes the critical need for early maternal screening for toxoplasmosis.
- * Recommends comprehensive, long-term follow-up for infants with suspected or confirmed congenital toxoplasmosis.
- * Informs public health strategies for managing congenital toxoplasmosis in Brazil and similar settings.
Abstract:
This is the first report of congenital toxoplasmosis in dizygotic twins in Brazil. We emphasize the need for early diagnosis of the mother and follow-up of children with suspected or confirmed infection from birth to adolescence, in order to avoid the hazard and damage from congenital toxoplasmosis.
More Related Videos
Related Concept Videos
01:28Toxoplasmosis
Toxoplasmosis, a zoonotic disease caused by the protozoan Toxoplasma gondii, poses significant public health challenges globally due to its high seroprevalence and varied clinical manifestations. As an obligate intracellular parasite, T. gondii can infect all warm-blooded vertebrates, but felids are its only definitive hosts, shedding unsporulated oocysts into the environment. Humans typically acquire the infection through ingestion of tissue cysts in undercooked meat or oocysts from...
01:22American Trypanosomiasis
Chagas disease, or American trypanosomiasis, is a vector-borne parasitic infection caused by Trypanosoma cruzi, a flagellated protozoan (kinetoplastid) of the family Trypanosomatidae. The disease is endemic in Latin America, although cases are increasingly reported worldwide due to human migration. Transmission most commonly occurs when feces of infected triatomine bugs contaminate bite wounds or mucosal surfaces; additional routes include congenital, transfusional, transplant-related, and oral...
01:07Teratogenicity
The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
01:18Trichomoniasis
Trichomonas vaginalis is a flagellated protozoan parasite and the causative agent of trichomoniasis, one of the most prevalent non-viral sexually transmitted infections in the United States. This extracellular parasite primarily colonizes the lower genitourinary tract in women—particularly the vagina—and in men, the urethra and prostate. Its structural and functional adaptations enable its survival, motility, and pathogenicity within the host environment.Structural Features and Host EntryT.
01:30Leishmaniasis
Leishmaniasis is a protozoal disease caused by species of the genus Leishmania and transmitted through the bite of infected female sandflies. The parasite exists in two principal morphological forms during its life cycle. A sandfly acquires intracellular amastigotes from an infected reservoir host, such as a dog. Within the sandfly, these forms differentiate into motile, flagellated promastigotes. During a subsequent blood meal, promastigotes are injected into the human host, where they...
01:28Pulmonary Tuberculosis II
Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...