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HIV prevention with severely mentally ill men: a randomised controlled trial
A Berkman1, D J Pilowsky, P A Zybert
1Mailman School of Public Health, Columbia University, New York, NY 10032, USA. ab376@columbia.edu
AIDS Care
|May 17, 2007
Summary
An enhanced intervention did not significantly reduce HIV sexual risk behaviors in men with severe mental illness. A trend toward risk reduction was observed at six months but not maintained at 12 months.
Area of Science:
- Public Health
- Mental Health Research
- Clinical Trials
Background:
- Men with severe mental illness are at higher risk for HIV.
- Previous interventions have shown promise in reducing sexual risk behaviors.
Purpose of the Study:
- To test the efficacy of an enhanced intervention to reduce HIV sexual risk behaviors.
- To assess long-term effects of the intervention over 12 months.
Main Methods:
- A randomized clinical trial with 149 men aged 18-59.
- Intervention group received enhanced program; control group did not.
- Sexual risk behaviors assessed every three months using Vaginal Episodes Equivalent (VEE) score.
Main Results:
- No significant differences in sexual risk behaviors with casual partners between groups.
- A trend toward risk reduction at six months (p=0.06) was not statistically significant.
- Observed risk reduction, if any, was not maintained at 12 months.
Conclusions:
- The enhanced intervention did not demonstrate statistically significant efficacy in reducing HIV sexual risk behaviors.
- The trial may have been underpowered to detect a true reduction in risk.
- Further research is needed to explore sustained risk reduction strategies.
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