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Related Experiment Video

Updated: Jul 14, 2026

Quantitation of Intra-peritoneal Ovarian Cancer Metastasis

Quantitation of Intra-peritoneal Ovarian Cancer Metastasis

Published on: July 18, 2016

Ovarian pregnancy without definitive pathologic confirmation: a case report.

Alireza Abidi¹, Rebecca Gordon, Mary Beth Harman

¹Department of Obstetrics and Gynecology, Bridgeport Hospital, Yale School of Medicine, Connecticut, USA. abidiali@hotmail.com

The Journal of Reproductive Medicine

|May 18, 2007

Summary

Ovarian pregnancy is a rare ectopic pregnancy. The study suggests reconsidering the historical Spiegelberg criteria for diagnosing ovarian pregnancy due to diagnostic challenges.

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Area of Science:

Reproductive Medicine
Gynecologic Pathology
Surgical Gynecology

Background:

Ovarian pregnancy is an exceptionally rare form of ectopic pregnancy.
Diagnosis traditionally relies on Spiegelberg criteria (1878), requiring specific pathological features.
These criteria can be challenging to meet definitively in all ovarian pregnancy cases.

Observation:

A case presented with clinical signs suggestive of ovarian pregnancy.
Surgical exploration indicated an ovarian ectopic pregnancy.
Pathological examination did not strictly adhere to the established Spiegelberg criteria.

Findings:

Despite not meeting exact pathological criteria, the clinical presentation and follow-up confirmed an ovarian pregnancy.
The case highlights discrepancies between clinical suspicion and strict pathological definitions.
Alternative diagnoses were excluded, reinforcing the ovarian origin.

Implications:

The findings suggest the Spiegelberg criteria for ovarian pregnancy may require re-evaluation and potential modification.
Clinical judgment and comprehensive follow-up are crucial when pathological criteria are ambiguous.
Revised diagnostic guidelines could improve accuracy in identifying rare ovarian pregnancies.