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Updated: Jul 14, 2026
05:44
Skin Biopsy for Diagnosing Discoid Lupus Erythematosus
Published on: June 10, 2025
[Oral involvement in lymphomatoid papulosis]
C Serra-Guillén1, C Requena, A Alfaro
1Servicio de Dermatología, Instituto Valenciano de Oncología, Valencia, España. cserraguillen@hotmail.com
Actas Dermo-Sifiliograficas
|May 18, 2007
Summary
Lymphomatoid papulosis, a rare skin T cell lymphoma, can affect the oral mucosa, typically as ulcers. This case highlights oral involvement in a patient with a prior diagnosis of this indolent cutaneous lymphoma.
Area of Science:
- Dermatology
- Oncology
- Pathology
Background:
- Lymphomatoid papulosis is an indolent cutaneous T cell lymphoma.
- It typically presents as recurrent, self-limiting necrotic papules.
- Mucosal involvement is rare, usually manifesting as ulcers in diagnosed patients.
Observation:
- A patient with a history of lymphomatoid papulosis developed two ulcerated lesions on the tongue.
- Histopathological examination revealed an infiltrate of CD30+ atypical lymphocytes and mixed inflammatory cells.
Findings:
- The tongue lesions were confirmed as oral involvement by lymphomatoid papulosis.
- This presentation is rare but consistent with known patterns of extranodal extension.
Implications:
- This case expands the understanding of lymphomatoid papulosis manifestations.
- Highlights the importance of considering oral lesions in patients with known lymphomatoid papulosis.
- Emphasizes the need for thorough histopathological evaluation of oral lesions in this context.
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