Miniaturized, on-head, invasive electrode connector integrated EEG data acquisition system

Area of Science:

• Neuroscience
• Biomedical Engineering

Background:

• Current intracranial electroencephalogram (EEG) systems utilize numerous wires, leading to noise and restricted patient mobility.
• These limitations impact patient compliance and complicate monitoring procedures.

Purpose of the Study:

• To develop a miniaturized intracranial EEG monitoring system.
• To overcome the drawbacks of traditional EEG systems by integrating electronics directly onto the head.

Main Methods:

• Developed a head-mounted 128-channel system by integrating instrumentation amplifiers and multiplexers into electrode connectors.
• Assembled 8-channel modular units connected to a 16:1 multiplexer manifold, resulting in a compact 55 cm³ system.
• Utilized a single 6-conductor, 30m cable for signal transmission to a remote data acquisition system.

Main Results:

• Successfully integrated miniaturized EEG amplifiers and analog multiplexers into electrode connectors.
• Achieved amplification and analog multiplexing of up to 128 EEG channels directly on the patient's head.
• Obtained amplified EEG data through a single long wire, simplifying the setup.

Conclusions:

• The miniaturized system has the potential to reduce artifacts and simplify troubleshooting in invasive EEG recordings.
• This technology can lower nursing care requirements and increase patient compliance.
• Miniaturization advances intracranial EEG monitoring, enabling capacities exceeding 128 channels.