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Related Concept Videos

Brain Imaging01:14

Brain Imaging

Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans),  magnetic resonance imaging (MRI),  functional magnetic resonance imaging (fMRI), and Transcranial Magnetic Stimulation (TMS).
Blood and Nerve Supply to the Bones01:29

Blood and Nerve Supply to the Bones

Bones are dynamic organs that require a rich supply of oxygen and nutrients. Around 5% to 10% of the cardiac output supplies blood to the bones. A typical long bone has three main sources: the nutrient artery, the metaphyseal and epiphyseal arteries, and the periosteal arteries.
Nutrient Artery
The nutrient artery is the main blood vessel that enters the diaphysis via the nutrient foramen. While most long bones have only one nutrient foramen, large bones, such as the femur, may have two. This...
Pain01:20

Pain

Pain serves as a critical warning signal that alerts the body to potential or actual harm. When mechanical pressure on the skin is intense, such as from a sharp pinch, the sensation transitions from touch to pain. Similarly, extreme temperatures, like a hot pot handle, convert the sensation of heat into pain. Pain can also result from overstimulation of other senses, such as blinding light, loud noise, or the intense heat from habañero peppers. This ability to sense pain is essential for...

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Related Experiment Video

Updated: Jul 14, 2026

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
10:39

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache

Published on: June 2, 2014

Neuroimaging: visualising the brain in pain.

A May1

  • 1Department of Systems Neuroscience, Universitäts-Krankenhaus Eppendorf, Martinistr. 52, D-20246 Hamburg, Germany. a.may@uke.uni-hamburg.de

Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
|May 18, 2007
PubMed
Summary

Neuroimaging studies reveal the brain

Area of Science:

  • Neuroscience
  • Pain Research
  • Medical Imaging

Background:

  • Neuroimaging has transformed the understanding of pain physiology and chronic pain pathophysiology.
  • Research has identified a complex brain network, the pain matrix, involved in pain processing.
  • Existing studies offer insights but more brain imaging research on chronic pain is needed.

Purpose of the Study:

  • To explore the role of neuroimaging in understanding pain.
  • To investigate the neural mechanisms underlying chronic pain conditions.
  • To highlight the need for further brain imaging research in chronic pain.

Main Methods:

  • Utilizing neuroimaging techniques (e.g., fMRI, PET) to study pain responses.
  • Analyzing brain activity and structure in experimental and clinical pain models.

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Real-time Video Projection in an MRI for Characterization of Neural Correlates Associated with Mirror Therapy for Phantom Limb Pain
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Autoradiographic Measurements of [14C]-Iodoantipyrine in Rat Brain Following Central Post-Stroke Pain
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  • Reviewing existing neuroimaging and pharmacological studies on pain circuitry.

    • Main Results:

    • Neuroimaging has elucidated the physiological responses to pain.
    • A complex network of brain structures (pain matrix) is involved in pain perception.
    • Chronic pain involves functional and structural plasticity in the nervous system.

    Conclusions:

    • Neuroimaging has significantly advanced pain research and understanding of chronic pain.
    • The chronification of pain involves neuroplastic changes in both central and peripheral nervous systems.
    • Further neuroimaging studies are essential for a comprehensive understanding of chronic pain.