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Updated: Jul 14, 2026

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3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
Published on: June 2, 2014
Basilar-type migraine responsive to lamotrigine: three case reports.
F d'Onofrio1, D Cologno, V Petretta
1Institute of Neurology, San G. Moscati Hospital, Avellino, Italy.
Summary
Lamotrigine may effectively prevent basilar-type migraine (BM) aura symptoms. This study explored its use in three female BM patients, showing potential therapeutic benefits for this specific migraine subtype.
Area of Science:
- Neurology
- Neuroscience
- Clinical Medicine
Background:
- Basilar-type migraine (BM) is a distinct subtype of migraine with aura, originating from the brainstem.
- BM is characterized by aura symptoms without motor deficits, differentiating it from hemiplegic migraines.
- Lamotrigine has demonstrated efficacy in preventing typical migraine aura and some BM cases.
Observation:
- This study investigated the use of lamotrigine in three female patients diagnosed with basilar-type migraine.
- The treatment aimed to assess the potential of lamotrigine in managing the aura symptoms associated with BM.
Findings:
- Lamotrigine was administered to three female patients experiencing basilar-type migraine.
- The study observed the effects of lamotrigine on the frequency and severity of aura symptoms in these patients.
Implications:
- Findings suggest lamotrigine could be a viable preventive treatment for basilar-type migraine aura.
- Further research is warranted to confirm lamotrigine's efficacy and safety profile for BM.
- This study contributes to understanding therapeutic options for complex migraine subtypes.
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