Related Experiment Video
Updated: Jul 14, 2026

Methods for Analyzing the Impacts of Natural Uranium on In Vitro Osteoclastogenesis
Published on: January 30, 2018
A review of depleted uranium biological effects: in vitro and in vivo studies
Alexandra C Miller1, David McClain
1Uniformed Services University of the Health Sciences, Armed Forces Radiobiology Research Institute, 8901 Wisconsin Avenue, Building 42, Bethesda, MD 20889-5603, USA. millera@afrri.usuhs.mil
Abstract:
The use of depleted uranium in armor-penetrating munitions remains a source of controversy because of the numerous unanswered questions about its long-term health effects. Although no conclusive epidemiologic data have correlated DU exposure to specific health effects, studies using cultured cells and laboratory rodents continue to suggest the possibility of leukemogenic, genetic, reproductive, and neurological effects from chronic exposure. Until issues of concern are resolved with further research, the use of depleted uranium by the military will continue to be controversial.
More Related Videos
Related Concept Videos
Microbial Bioremediation of Uranium
Biological Effects of Radiation
Toxicity Testing in Animals
Equivalence: In Vitro and In Vivo Bioequivalence

