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Related Experiment Video

Updated: Jun 30, 2026

miRNA Expression Analyses in Prostate Cancer Clinical Tissues
11:29

miRNA Expression Analyses in Prostate Cancer Clinical Tissues

Published on: September 8, 2015

Prostate cancer.

David F Penson1, June M Chan,

  • 1Departments of Urology and Preventive Medicine, Keck School of Medicine, University of Southern California, 1441 Eastlake Avenue, Los Angeles, CA 90089, USA. penson@usc.edu

The Journal of Urology
|May 19, 2007
PubMed
Summary
This summary is machine-generated.

Prostate cancer burden in the US increased significantly in the PSA era, with rising incidence and costs despite improved survival. Further research is needed to ensure appropriate healthcare resource allocation for this common cancer.

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Published on: March 6, 2018

Area of Science:

  • Urologic Oncology
  • Cancer Epidemiology
  • Health Services Research

Background:

  • Prostate cancer remains a significant public health concern in the United States.
  • Understanding trends in incidence, treatment, and economic impact is crucial for effective management.

Purpose of the Study:

  • To quantify the burden of prostate cancer in the US.
  • To analyze trends in incidence, disease stage at diagnosis, survival rates, and healthcare resource utilization.
  • To estimate the economic impact of prostate cancer.

Main Methods:

  • Analysis of national data on prostate cancer incidence, stage, survival, and healthcare resource use.
  • Estimation of economic expenditures related to prostate cancer treatment.

Main Results:

  • Prostate cancer incidence peaked in 1992, then rose annually through 2000. Marked stage migration and improved 5-year survival were observed.
  • Hospitalizations decreased, while radical prostatectomy rates shifted towards younger men. Significant ethnic and regional variations were noted.
  • Total medical expenditures for prostate cancer treatment increased by 30% from 1994 to 2000, reaching $1.3 billion.

Conclusions:

  • The burden of prostate cancer has substantially increased in the prostate-specific antigen (PSA) era.
  • Further research is essential to optimize the use of healthcare resources for prostate cancer diagnosis and treatment.