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Related Experiment Videos

Atypical mediastinal lipomatosis.

Saurabh S Dhawan1, Rami Khouzam

  • 1Department of Internal Medicine, University of Tennessee Health Science Center, Memphis, Tennessee, USA.

Heart & Lung : the Journal of Critical Care
|May 19, 2007
PubMed
Summary

This study reports a rare case of mediastinal lipomatosis, a condition of excess fat in the chest, in an elderly male without obesity or steroid use. Diagnostic imaging confirmed the fatty infiltration, highlighting an unusual presentation of this condition.

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Area of Science:

  • Cardiology
  • Radiology
  • Pathology

Background:

  • Mediastinal lipomatosis is a rare condition characterized by excessive fat accumulation in the mediastinum.
  • It is often associated with endogenous or exogenous steroid excess or obesity.
  • This case presents a unique instance without these typical risk factors.

Observation:

  • An elderly male patient presented with dyspnea on exertion.
  • Chest radiography revealed an enlarged cardiac silhouette with a characteristic "double contour" effect.
  • Transthoracic echocardiography suggested diffuse pericardial fatty infiltration distorting the left atrium.

Findings:

  • Computed tomography of the chest confirmed mediastinal lipomatosis by measuring radiodensity in Hounsfield units.
  • Serum cortisol levels were within the normal range.

Related Experiment Videos

  • This represents the second reported case of mediastinal lipomatosis in the absence of steroid excess or obesity.
  • Implications:

    • This case expands the understanding of the potential etiologies and presentations of mediastinal lipomatosis.
    • It underscores the importance of considering rare diagnoses even in the absence of typical risk factors.
    • Advanced imaging techniques are crucial for accurate diagnosis and characterization of mediastinal lipomatosis.