Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Less symptomatic hypotension using blood volume controlled ultrafiltration.

S Stiller1, D Wirtz, F Waterbär

  • 1Medical Clinic II, Technical University, Aachen, Germany.

ASAIO Transactions
|July 1, 1991
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Durvalumab with or without tremelimumab in combination with chemotherapy in first-line metastatic non-small-cell lung cancer: outcomes by tumor mutational burden in POSEIDON.

ESMO open·2025
Same author

Durvalumab, with or without tremelimumab, plus platinum-etoposide in first-line treatment of extensive-stage small-cell lung cancer: 3-year overall survival update from CASPIAN.

ESMO open·2022
Same author

Outcomes with durvalumab after chemoradiotherapy in stage IIIA-N2 non-small-cell lung cancer: an exploratory analysis from the PACIFIC trial.

ESMO open·2022
Same author

Osimertinib versus platinum-pemetrexed for patients with EGFR T790M advanced NSCLC and progression on a prior EGFR-tyrosine kinase inhibitor: AURA3 overall survival analysis.

Annals of oncology : official journal of the European Society for Medical Oncology·2020
Same author

How Imaging Can Assist with Diagnosis and Monitoring of Disease in Myositis.

Current rheumatology reports·2020
Same author

Myeloid Sarcomas Causing Unilateral Cranial Nerve Palsies in a Patient with Relapsed Acute Myeloblastic Leukemia.

Case reports in hematology·2020
Same journal

Extracorporeal membrane oxygenation as a means of stabilizing and transporting high risk neonates.

ASAIO transactions·1991
Same journal

Pumping capabilities of the latissimus dorsi and rectus abdominis muscles wrapped around a valved pouch in a mock circulatory system.

ASAIO transactions·1991
Same journal

Causes of intraaortic balloon leaks.

ASAIO transactions·1991
Same journal

Influence of centrifugal blood pumps on the elasticity of erythrocytes.

ASAIO transactions·1991
Same journal

Reuse of "highly permeable" dialyzers with peroxyacetic acid as sole cleansing and disinfecting agent.

ASAIO transactions·1991
Same journal

Comparison of 50% dextrose water, 25% mannitol, and 23.5% saline for the treatment of hemodialysis-associated muscle cramps.

ASAIO transactions·1991
See all related articles

Blood volume-controlled ultrafiltration (UF) reduces dialysis hypotension. This method adapts the ultrafiltration rate to blood volume changes, leading to fewer side effects and optimized dialysis therapy.

Area of Science:

  • Nephrology
  • Biomedical Engineering
  • Physiology

Background:

  • Symptomatic hypotension is a common complication during dialysis therapy.
  • Ultrafiltration (UF) is essential for fluid removal but can cause adverse effects.
  • Current dialysis protocols often use a constant ultrafiltration rate (UFR).

Purpose of the Study:

  • To develop and evaluate a blood volume (BV)-controlled UF system.
  • To adapt UFR based on continuous BV monitoring.
  • To minimize hypotensive episodes and muscle cramps during dialysis.

Main Methods:

  • Utilized hemoglobinometry for continuous blood volume monitoring.
  • Implemented a control system to adjust UFR based on a predefined BV profile.
  • Compared BV-controlled UF with conventional constant UFR in 10 dialysis patients.

Related Experiment Videos

Main Results:

  • The BV-controlled UF method significantly reduced hypotensive periods.
  • Muscle cramps were less frequent with the controlled UF approach.
  • Achieved target dry weight within the specified time.

Conclusions:

  • Blood volume-controlled ultrafiltration is a promising strategy for optimizing dialysis.
  • This method enhances patient tolerance and reduces adverse events.
  • Continuous BV monitoring allows for personalized and safer fluid management during dialysis.