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Related Concept Videos

Dialysis01:15

Dialysis

Dialysis is a diffusion-based purification process that separates analyte molecules from a complex matrix. This is accomplished by allowing molecules in the solution to pass through a semipermeable membrane into a liquid on the other side. The membrane is usually made of cellulose acetate or cellulose nitrate, and the second liquid must be miscible with the solution. Ions (e.g., chloride or sodium) or organic molecules (e.g., glucose) can pass through the membrane pores, which generally have...
Dialysis01:27

Dialysis

Renal failure occurs when the kidneys lose their ability to filter waste products from the blood effectively. It can be classified into two types: acute renal failure (ARF) and chronic renal failure (CRF).
Acute kidney injury develops suddenly and can be caused by pre-renal causes (e.g., hypovolemia, shock), intrinsic renal causes (e.g., acute tubular necrosis), or post-renal causes (e.g., urinary obstruction). In contrast, chronic renal failure progresses gradually over time and is often...
Extracorporeal Removal of Drugs: Peritoneal Dialysis and Hemodialysis01:30

Extracorporeal Removal of Drugs: Peritoneal Dialysis and Hemodialysis

Patients with end-stage renal disease (ESRD) or those experiencing drug overdose often require extracorporeal methods to eliminate accumulated drugs and metabolites. Hemoperfusion, hemofiltration, and dialysis are the primary techniques to rapidly remove harmful substances without disrupting the patient's fluid and electrolyte balance. For those with compromised renal function, dosage adjustments of concurrent medications may be necessary during extracorporeal drug removal.Dialysis is a process...
Peritoneal Dialysis II: Peritoneal Dialysis Systems and Complications01:25

Peritoneal Dialysis II: Peritoneal Dialysis Systems and Complications

Peritoneal dialysis (PD) is a medical process that removes waste products and excess fluid from the body using the peritoneal membrane as a natural filter.Peritoneal Dialysis MethodsSeveral methods can be used for peritoneal dialysis, including Acute Intermittent Peritoneal Dialysis, Continuous Ambulatory Peritoneal Dialysis, and Automated Peritoneal Dialysis, also known as Continuous Cyclic Peritoneal Dialysis.Acute Intermittent Peritoneal Dialysis (AIPD) is used for patients with uremic...
Hemodialysis I: Introduction01:25

Hemodialysis I: Introduction

Hemodialysis (HD) is a medical treatment that artificially removes waste products, excess fluids, and toxins from the blood when the kidneys are no longer able to perform these functions effectively. In this process, blood is filtered through a semipermeable membrane, allowing for the selective removal of waste while preserving necessary components like blood cells and proteins. Hemodialysis is typically performed in patients with end-stage renal disease (ESRD) or severe kidney...
Hemodialysis II: Procedure and Complications01:24

Hemodialysis II: Procedure and Complications

DialyzersA hemodialysis (HD) dialyzer is a plastic cartridge containing thousands of parallel hollow fibers, which serve as semipermeable membranes. These fibers are typically made from cellulose-based or other synthetic materials. During HD, blood is pumped into the top of the cartridge and distributed among these fibers. Simultaneously, dialysis fluid, known as dialysate, is introduced into the bottom of the cartridge, bathing the outside of the fibers. Across the semipermeable membrane,...

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Related Experiment Video

Updated: Jul 18, 2026

Epithelial Cell Repopulation and Preparation of Rodent Extracellular Matrix Scaffolds for Renal Tissue Development
09:43

Epithelial Cell Repopulation and Preparation of Rodent Extracellular Matrix Scaffolds for Renal Tissue Development

Published on: August 10, 2015

Determinants of dialyzer reuseability.

S G Sievers1, J L Stack, W F Piering

  • 1Department of Medicine, Medical College of Wisconsin, Milwaukee 53226.

ASAIO Transactions
|July 1, 1991
PubMed
Summary

Dialyzer reuse in hemodialysis patients varies significantly. Diabetic patients and those with higher white blood cell counts experience fewer dialyzer reuses, highlighting key factors influencing this practice.

Area of Science:

  • Nephrology
  • Medical Technology

Background:

  • Dialyzer reuse is a common practice in hemodialysis to reduce costs.
  • Variability exists in the number of times dialyzers can be safely reused.
  • Factors influencing dialyzer reuseability require further investigation.

Purpose of the Study:

  • To investigate the factors affecting dialyzer reuseability in hemodialysis patients.
  • To compare dialyzer reuse rates between diabetic and non-diabetic patients.

Main Methods:

  • Observational study involving 54 hemodialysis patients who reused their dialyzers.
  • Analysis of patient data including heparin dose, white blood cell count, and diabetes status.
  • Statistical analysis to determine correlations between patient factors and dialyzer reuse rates.

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Epithelial Cell Repopulation and Preparation of Rodent Extracellular Matrix Scaffolds for Renal Tissue Development
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Main Results:

  • Average dialyzer reuse was significantly lower in diabetic patients (5.1 reuses) compared to non-diabetic patients (7.8 reuses).
  • Higher white blood cell counts were inversely correlated with dialyzer reuseability.
  • Lower heparin doses (U/kg/min) were directly correlated with lower reuseability.
  • In non-diabetics, heparin dose was the primary determinant of reuse; in diabetics, white blood cell count was the major determinant.

Conclusions:

  • Dialyzer reuseability is diminished in diabetic patients.
  • Patients with higher white blood cell counts and those on lower heparin doses exhibit reduced dialyzer reuseability.
  • Further research is needed to fully understand the determinants of dialyzer reuseability.