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Published on: August 24, 2019
Appendiceal mucocoeles and pseudomyxoma peritonei
Anupam Dixit1, John H P Robertson, Satvinder S Mudan
1Colorectal Department, The London Clinic, 20 Devonshire Place, London W1G 6BW, United Kingdom. dixitanupam@hotmail.com
Abstract:
Mucocoele of the appendix occurs when obstruction of the appendiceal lumen results in mucus accumulation and consequent abnormal dilatation. The most important aetiology, from a surgical perspective, is either mucinous cystadenoma or cystadenocarcinoma. In the latter, a spontaneous or iatrogenic rupture of the mucocoele can lead to mucinous intraperitoneal ascites, a syndrome known as pseudomyxoma peritonei. Optimal management of mucoceles is achieved through accurate preoperative identification and subsequent careful resection. We report two cases and subsequently discuss the clinical presentation of mucocoeles, their association with pseudomyxoma peritonei and an optimal management of both conditions.
Insights
Appendiceal mucoceles, caused by mucus buildup, require accurate diagnosis and surgical resection. Rupture can lead to pseudomyxoma peritonei, necessitating careful management of both conditions.
Area of Science:
- Gastroenterology
- Surgical Oncology
Background:
- Appendiceal mucoceles result from appendiceal lumen obstruction, leading to mucus accumulation and dilatation.
- Key etiologies include mucinous cystadenoma and cystadenocarcinoma, with implications for pseudomyxoma peritonei development.
Observation:
- Presents two cases of appendiceal mucoceles.
- Discusses clinical presentation, association with pseudomyxoma peritonei, and optimal management strategies.
Findings:
- Accurate preoperative identification is crucial for effective surgical management.
- Careful resection is the optimal approach for managing appendiceal mucoceles and preventing complications.
Implications:
- Highlights the importance of distinguishing between benign and malignant mucinous appendiceal lesions.
- Emphasizes the need for a comprehensive approach to managing mucoceles and preventing pseudomyxoma peritonei.
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