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Related Experiment Videos

Anesthetic deaths in a developing country.

Mueenullah Khan1, Fauzia A Khan

  • 1Dept. of Anaesthesia, Aga Khan Univ. Karachi, Pakistan. mueen.khan@aku.edu

Middle East Journal of Anaesthesiology
|May 22, 2007
PubMed
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Anesthesia contributed to 11% of perioperative deaths, with preventable factors identified. Mortality rates decreased significantly from 1992-2003, highlighting improvements in anesthetic safety.

Area of Science:

  • Anesthesiology
  • Perioperative Medicine
  • Public Health

Background:

  • Limited data exists on anesthesia-related mortality in developing countries.
  • Improving perioperative safety and quality of care necessitates understanding anesthesia's contribution to mortality.
  • This study addresses the data gap by examining anesthetic mortality in a university hospital in a developing nation.

Purpose of the Study:

  • To determine the incidence and causes of anesthesia-related mortality.
  • To identify factors contributing to perioperative deaths within 24 hours of anesthesia.
  • To compare findings with international studies from developed and developing countries.

Main Methods:

  • Retrospective review of patient deaths within 24 hours of anesthesia from 1992-2003.

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  • Data collected as part of departmental quality assurance.
  • Analysis included crude mortality, anesthesia's sole/partial responsibility, and contributing factors.
  • Main Results:

    • A crude mortality rate of 3.14 per 10,000 anesthetics was observed.
    • Anesthesia was solely responsible for 0.35 per 10,000 and partially responsible for 0.7 per 10,000 deaths.
    • Mortality decreased from 0.68 per 10,000 (1992-1998) to 0.18 per 10,000 (1999-2003).
    • Higher mortality was linked to advanced age, higher ASA status, emergency, and complex surgeries.
    • Preventable factors included human error, inadequate preparation/postoperative care, and lack of supervision.

    Conclusions:

    • Anesthesia's contribution to perioperative mortality is significant but potentially reducible.
    • Improvements in anesthetic safety were observed over the study period.
    • Addressing human factors, preparation, postoperative care, and supervision is crucial for reducing avoidable anesthetic deaths.