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Related Experiment Videos

A unique, efficient, implantable, electromechanical, total artificial heart.

S Takatani1, M Shiono, T Sasaki

  • 1Department of Surgery, Baylor College of Medicine, Houston, Texas 77030.

ASAIO Transactions
|July 1, 1991
PubMed
Summary
This summary is machine-generated.

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A novel electromechanical total artificial heart (TAH) was developed for permanent use. This compact, one-piece device demonstrated effective pumping function and good fit for heart transplant recipients.

Area of Science:

  • Biomedical Engineering
  • Cardiovascular Devices
  • Implantable Devices

Background:

  • End-stage heart failure necessitates advanced circulatory support.
  • Existing artificial heart technologies face challenges in long-term durability and efficiency.
  • The development of a compact, implantable total artificial heart is crucial for patient survival.

Purpose of the Study:

  • To develop and evaluate a novel, completely implantable, one-piece electromechanical total artificial heart (TAH) for permanent human use.
  • To assess the device's pumping performance, efficiency, and anatomical fit.

Main Methods:

  • Design and construction of a one-piece electromechanical TAH featuring conically shaped pusher-plate blood pumps and a compact actuator.
  • Utilized a direct current brushless motor and a planetary roller screw for efficient motion conversion.

Related Experiment Videos

  • Evaluated pump performance including flow rates, preload, afterload, and net efficiency.
  • Assessed anatomical fit within the pericardial space of heart transplant recipients.

    • Main Results:

    • The developed TAH has a diameter of 97 mm and a central thickness of 82 mm, weighing 620 g with a displaced volume of 510 ml.
    • The pump achieved flow rates of 3-8 L/min against an afterload of 100 mmHg with a preload of 1-15 mmHg.
    • Net efficiency ranged from 15% to 18%.
    • Demonstrated good anatomical fit in the pericardial space of a 77 kg heart transplant recipient.

    Conclusions:

    • The developed electromechanical total artificial heart is a promising compact, one-piece device for permanent circulatory support.
    • The device exhibits effective pumping capabilities and suitable anatomical fit for potential clinical application in heart failure patients.
    • Further research and clinical trials are warranted to validate its long-term efficacy and safety.