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Updated: Jul 14, 2026

Expression of Transgenes in Native Bladder Urothelium Using Adenovirus-Mediated Transduction
Published on: October 6, 2022
Granular cell tumor of the urethra
Hitoshi Yokoyama1, Kazuhiko Kontani, Itsuki Komiyama
1Department of Urology, National Matsumoto University, Matsumoto City, Nagano, Japan. h-yokoyama0608@ych.pref.yamanashi.jp
Abstract:
A 38-year-old woman was referred for urethral tumor treatment. Needle biopsy of the tumor was performed. Histologically, the tumor was composed of large polygonal cells with eosinophilic and periodic acid-Schiff (PAS)-positive granular cytoplasm, indistinct cell margins and small round central nuclei. Immunohistochemical staining for S100 protein, vimentin, and neuron-specific enolase (NSE) was positive, indicating that it was a granular cell tumor. Excision of the tumor including the urethra and appendicovesicostomy using the Mitrofanoff principle were performed. There has been no tumor recurrence in the 8 months after the operation.
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