Chemokine receptor CCR5 in interferon-treated multiple sclerosis

F Sellebjerg1, T B Kristiansen, P Wittenhagen

  • 1The MS Clinic, Department of Neurology, Glostrup Hospital, University of Copenhagen, 57 Nordre Ringvej, DK-2600 Glostrup, Denmark. sellebjerg@dadlnet.dk

Summary

In multiple sclerosis (MS) patients treated with interferon-beta, higher monocyte CCR5 expression weakly correlated with short-term relapse risk. However, CCR5 genetic variations did not impact relapse risk, suggesting CCR5 may indicate disease activity.

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