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Related Concept Videos

What is Cancer?02:12

What is Cancer?

Cells and tissues must meticulously coordinate their activities for the normal functioning of the human body. Therefore, they exhibit socially responsible behavior - resting, growing, dividing, differentiating, or dying - for the organism’s benefit. Cancer arises when cells divide uncontrollably and invade other tissues or organs.
Although people have known about cancer for centuries, it was only in 1761 that Giovanni Morgagni of Padua performed a detailed autopsy of patients who died from...
What is Cancer?02:12

What is Cancer?

Cells and tissues must meticulously coordinate their activities for the normal functioning of the human body. Therefore, they exhibit socially responsible behavior - resting, growing, dividing, differentiating, or dying - for the organism’s benefit. Cancer arises when cells divide uncontrollably and invade other tissues or organs.
Although people have known about cancer for centuries, it was only in 1761 that Giovanni Morgagni of Padua performed a detailed autopsy of patients who died from...
Rous Sarcoma Virus (RSV) and Cancer01:03

Rous Sarcoma Virus (RSV) and Cancer

Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
RSV is a retrovirus that contains two copies of a plus-strand  RNA genome. Its genome consists of four main open...
Rous Sarcoma Virus (RSV) and Cancer01:03

Rous Sarcoma Virus (RSV) and Cancer

Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
RSV is a retrovirus that contains two copies of a plus-strand  RNA genome. Its genome consists of four main open...
Treatment Resistant Cancers02:56

Treatment Resistant Cancers

Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...
Cancer02:18

Cancer

Cancers arise due to mutations in genes involved in the regulation of cell division, which leads to unrestricted cell proliferation. Modern science and medicine have made great strides in the understanding and treatment of cancer, including eradicating cancer in some patients. However, there is still no cure for cancer. This is largely due to the fact that cancer is a large group of many diseases.

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Related Experiment Videos

Symptom clusters in children with cancer.

Marilyn Hockenberry1, Mary C Hooke

  • 1Center for Research and Evidence-Based Practice, Texas Children's Hospital, Houston, TX, USA. mjhocken@txccc.org

Seminars in Oncology Nursing
|May 22, 2007
PubMed
Summary

Children with cancer experience distressing symptoms like fatigue, pain, and sleep issues that often occur together. Understanding these symptom clusters can improve quality of life and support development during treatment.

Area of Science:

  • Pediatric Oncology
  • Symptom Science
  • Childhood Cancer Research

Background:

  • Children undergoing cancer treatment frequently experience distressing symptoms such as fatigue, pain, and sleep disturbances.
  • These symptoms are prevalent and often co-occur, impacting a child's well-being and development.

Purpose of the Study:

  • To explore the common symptoms of fatigue, sleep disturbance, and pain in pediatric cancer patients.
  • To propose a framework for understanding the clustering of these interconnected symptoms.

Main Methods:

  • Review of published literature, including research articles and clinical studies.
  • Synthesis of clinical experience with pediatric cancer patients.

Main Results:

Related Experiment Videos

  • Symptoms like fatigue, pain, and sleep disturbance are common and distressing in children with cancer.
  • These symptoms rarely occur in isolation and may share common underlying biological or psychological mechanisms.
  • Conclusions:

    • Recognizing symptom clusters is crucial for improving the quality of life for children undergoing cancer treatment.
    • Understanding symptom relationships can help support a child's ongoing development during therapy.
    • Nurses play a vital role in recognizing and managing symptom distress in pediatric cancer patients.