Related Concept Videos
01:22Drug Delivery: Miscellaneous Routes
Drug delivery methods like oral inhalation, nasal sprays, transdermal patches, eye drops, intravitreal injection, and rectal administration provide localized effects with reduced toxicity.
Oral inhalation and nasal sprays swiftly transfer drugs across the respiratory epithelium's mucosal layer. Inhaled glucocorticoids and bronchodilators directly target lung conditions such as asthma, while fluticasone nasal spray mitigates allergic rhinitis.
Transdermal patches transport drugs through the...
Oral inhalation and nasal sprays swiftly transfer drugs across the respiratory epithelium's mucosal layer. Inhaled glucocorticoids and bronchodilators directly target lung conditions such as asthma, while fluticasone nasal spray mitigates allergic rhinitis.
Transdermal patches transport drugs through the...
01:28Parenteral Drug Delivery Systems: Injectables, Implants, and Infusion Devices
Parenteral drug delivery systems play a crucial role in modern therapeutics by enabling the direct administration of drugs into the systemic circulation, bypassing the gastrointestinal tract. These systems are particularly valuable for poorly absorbed oral medications that are unstable in the digestive environment or require rapid onset or sustained therapeutic levels. Delivery is achieved through intravenous, intramuscular, or subcutaneous routes, each selected based on the drug's properties...
01:29Drug Delivery: Parenteral Route
The parenteral route is a critical method of drug administration. It delivers compounds directly into the systemic circulation and bypasses the gastrointestinal tract. This approach is particularly advantageous for drugs that exhibit poor absorption or instability when administered orally.
There are three primary parenteral routes: intravenous (IV), intramuscular (IM), and subcutaneous (SC). The IV route introduces the drug directly into the bloodstream, ensuring immediate action. The IM route...
There are three primary parenteral routes: intravenous (IV), intramuscular (IM), and subcutaneous (SC). The IV route introduces the drug directly into the bloodstream, ensuring immediate action. The IM route...
01:27Tumor Immunotherapy
Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
01:25Routes of Drug Administration: Parenteral
The administration of drugs via parenteral routes allows for direct drug introduction into the systemic circulation, resulting in high bioavailability because the medication bypasses the harsh conditions of the gastrointestinal tract and hepatic metabolism.
The intravenous route (IV) of drug administration can be further categorized into two types. The bolus injection administers the entire dose rapidly, while an intravenous infusion slowly delivers smaller doses steadily.
The IV route is often...
The intravenous route (IV) of drug administration can be further categorized into two types. The bolus injection administers the entire dose rapidly, while an intravenous infusion slowly delivers smaller doses steadily.
The IV route is often...
You might also read
Related Articles
Articles linked to this work by shared authors, journal, and citation graph.
Sort by
Same author
Validation of clinical examination versus magnetic resonance imaging and arthroscopy for the detection of rotator cuff lesions.
Clinical rheumatology·2013
Same author
The assessment and management of chronic hamstring/posterior thigh pain.
Best practice & research. Clinical rheumatology·2007
Related Experiment Video
Updated: Jul 14, 2026
05:18
Ultrasound-Guided Needle Release Combined with Corticosteroid Injection for the Treatment of Supinator Syndrome
Published on: May 26, 2023
Injection therapies for soft-tissue lesions.
1Addenbrookes Hospital, Hills Road, Cambridge CB2 2QQ, UK. cathy.speed@btinternet.com
Best Practice & Research. Clinical Rheumatology
|May 22, 2007
Summary
This chapter reviews local injection therapies for musculoskeletal pain, including corticosteroids and dry needling. It discusses their mechanisms, side effects, and practical applications for soft-tissue conditions.
Area of Science:
- Orthopedics
- Pain Management
- Musculoskeletal Medicine
Background:
- Musculoskeletal pain syndromes are common.
- Local injection therapies are frequently used for pain management.
- Various substances and techniques are employed in these injections.
Purpose of the Study:
- To describe injection therapies for soft-tissue pain.
- To discuss the rationale, mechanisms, and adverse effects of these treatments.
- To critically review the existing literature and provide practical guidance.
Main Methods:
- Review of literature on local injection therapies.
- Discussion of corticosteroids, anesthetics, sclerosants, botulinum toxin, dry needling, and neural blockade.
- Critical analysis of treatment effects and side effects.
Main Results:
- Injection therapies offer diverse mechanisms for pain relief.
- Potential adverse effects need careful consideration.
- Evidence supports the use of specific injections for certain soft-tissue conditions.
Conclusions:
- Local injection therapies are valuable tools for managing soft-tissue pain.
- Further research is needed to optimize their application and understand their full potential.
- Practical guidelines are provided for clinicians.