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Updated: Jul 14, 2026

Positron Emission Tomography-based Dose Painting Radiation Therapy in a Glioblastoma Rat Model using the Small Animal Radiation Research Platform
Published on: March 24, 2022
Specifying carbon ion doses for radiotherapy: the heidelberg approach
Oliver Jäkel1, Daniela Schulz-Ertner, Jürgen Debus
1German Cancer Research Center (DKFZ), Dep. Medical Physics in Radiation Therapy (E040).
Abstract:
There are currently no guidelines for prescribing and reporting radiation therapy (RT) with ion beams. In this paper an overview over some technical aspects and their implication on ion RT are reported. This includes a discussion of the difference in the treatment planning systems currently used for active and passive beam shaping systems, aspects of patient positioning and target definition and dose prescription. Special emphasis is put on the questions arising from the use of the beam scanning methods in combination with biological treatment plan optimization, which is used in the German heavy ion therapy facility at GSI and will also be introduced at the hospital based facility in Heidelberg. Furthermore, the Heidelberg approach for the clinical dose prescription is compared with the methods developed at HIMAC in Chiba, Japan.

