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Related Concept Videos

Birth Control Methods01:22

Birth Control Methods

Vasectomy is a surgical form of male sterilization that involves severing and sealing the vasa deferentia, preventing sperm from mixing with semen during ejaculation. Because a vasectomy does not impact the testes' ability to produce testosterone, hormone levels, libido, and sexual function generally remain unchanged. While vasectomy is highly effective in preventing pregnancy, with a success rate near 99.85%, rare cases of recanalization (spontaneous reconnection) can occur. Although vasectomy...
Intrauterine Drug Delivery Systems01:21

Intrauterine Drug Delivery Systems

Controlled-release systems for intravaginal and intrauterine drug delivery have been developed primarily for the administration of contraceptive steroid hormones. These delivery routes circumvent first-pass hepatic metabolism, thereby enhancing bioavailability and allowing for reduced systemic dosages compared to oral administration. Such approaches contribute to improved therapeutic efficacy and patient compliance, particularly in long-term contraceptive regimens.Intravaginal Drug Delivery...
Infertility in Females01:28

Infertility in Females

Female infertility is defined as the inability to conceive after a year of regular, unprotected intercourse and affects about 10–15% of couples worldwide. The primary cause of female infertility is ovulatory disorders, which hinder the release of eggs. These disorders can be classified as hypothalamic amenorrhea, polycystic ovarian syndrome (PCOS), premature ovarian failure, and hyperprolactinemic anovulation disorders.
Endometriosis, a condition characterized by abnormal growth of endometrial...
Hormonal Control of the Ovarian Cycle01:30

Hormonal Control of the Ovarian Cycle

The ovarian cycle is meticulously regulated by the hypothalamic-pituitary-gonadal axis. This cycle orchestrates the release of a mature oocyte, essential for reproduction.
Before puberty, the hypothalamus releases GnRH in a low frequency, low amplitude pulsatile manner. This along with the immature hypothalamic-pituitary-gonadal axis activity, results in low estrogen levels and the absence of a fully functional ovarian cycle.  At puberty, GnRH secretion increases in both frequency and...
Infertility in Males01:23

Infertility in Males

Male infertility affects millions of couples worldwide, arising from various factors that impact different stages of the reproductive process. An endocrine imbalance resulting from conditions like hypogonadism, Klinefelter syndrome, or pituitary disorders can disrupt hormone levels and reduce sperm production. Testicular defects, such as tumors, cryptorchidism, atrophic testes, abnormal sperm morphology, and low sperm count or motility, may arise due to genetic factors, structural...
Hormonal Regulation of the Menstrual Cycle01:22

Hormonal Regulation of the Menstrual Cycle

The ovarian cycle regulates endometrial changes throughout a single menstrual cycle via the coordinated action of gonadotrophin-releasing hormone (GnRH) and gonadotrophins.
At puberty, GnRH begins a pulsatile release pattern, which triggers the anterior pituitary gland to secrete follicle-stimulating hormone (FSH) and luteinizing hormone (LH). The frequency and amplitude of GnRH pulses vary across the menstrual cycle, with faster pulses favoring LH release and slower pulses favoring FSH release.

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Introduction of Intracapsular Rotary-cut Procedures (IRCP): A Modified Hysteromyomectomy Procedures Facilitating Fertility Preservation
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Innovations in contraception: a review.

Robert K Zurawin1, Leslie Ayensu-Coker

  • 1Division of Pediatric and Adolescent Gynecology, Department of Obstetrics and Gynecology, Baylor College of Medicine, Houston, TX 77030-2305, USA. rzurawin@bcm.edu

Clinical Obstetrics and Gynecology
|May 22, 2007
PubMed
Summary

New contraceptive methods enhance safety and tolerability while maintaining efficacy. Innovations include novel hormonal formulations, improved oral contraceptive compliance strategies, and advanced delivery systems like patches, rings, and intrauterine devices.

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Area of Science:

  • Reproductive Health
  • Pharmacology
  • Gynecology

Background:

  • Traditional contraceptives face challenges with safety and tolerability.
  • There is a continuous need for improved contraceptive options.
  • Patient compliance remains a key factor in contraceptive effectiveness.

Purpose of the Study:

  • To review recent advancements in contraceptive technology.
  • To highlight new formulations and delivery systems.
  • To discuss methods aimed at improving user experience and adherence.

Main Methods:

  • Review of current literature on novel contraceptive agents and methods.
  • Discussion of hormonal modifications (estrogen, progestins) and their impact.
  • Analysis of non-hormonal and device-based contraceptive innovations.

Main Results:

  • Introduction of low/ultra-low dose estrogen and less-androgenic progestins.
  • Development of drospirenone and the Quick Start oral contraceptive method.
  • Emergence of contraceptive patch, vaginal ring, levonorgestrel intrauterine system, and hysteroscopic sterilization.

Conclusions:

  • New contraceptive developments offer improved safety and tolerability profiles.
  • These innovations aim to enhance efficacy and patient compliance.
  • A range of advanced options are now available to meet diverse patient needs.