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Related Concept Videos

Obsessive-Compulsive Disorder01:28

Obsessive-Compulsive Disorder

Obsessive-compulsive disorder (OCD) is a mental health condition characterized by recurrent obsessions, compulsions, or both, which consume significant time and interfere with daily functioning. Obsessions involve persistent, intrusive, and unwanted thoughts, images, or urges that evoke anxiety. Common examples include irrational fears of contamination or harm. Compulsions are repetitive behaviors or mental acts performed to reduce the anxiety caused by obsessions. For instance, individuals...
Diagnostic and Statistical Manual of Mental Disorders (DSM)01:27

Diagnostic and Statistical Manual of Mental Disorders (DSM)

The Diagnostic and Statistical Manual of Mental Disorders (DSM) serves as the primary classification system for mental health disorders, providing standardized diagnostic criteria for clinicians and researchers. First published by the American Psychiatric Association (APA) in 1952, the DSM has undergone several revisions to reflect evolving psychiatric understanding. The fifth edition, DSM-5, released in 2013, introduced key updates that expanded diagnostic categories and modified diagnostic...
Oppositional Defiant Disorder01:30

Oppositional Defiant Disorder

A persistent pattern of angry or irritable mood, defiant behavior, or vindictiveness characterizes Oppositional Defiant Disorder (ODD). Symptoms must occur over at least six months, involve interactions with individuals beyond siblings, and meet specific diagnostic criteria to be clinically significant. The disorder affects emotional regulation, social interactions, and behavior, often manifesting early in life and influencing long-term development and functioning.
Diagnostic Criteria and...
Personality Disorders: Dependent and Obsessive-Compulsive01:24

Personality Disorders: Dependent and Obsessive-Compulsive

Dependent personality disorder and obsessive-compulsive personality disorder are two separate psychological conditions that influence behavior, relationships, and overall life functioning. Though both involve maladaptive behaviors, their core characteristics and motivations differ significantly.
 Dependent Personality Disorder
Dependent personality disorder is characterized by an excessive reliance on others to manage various aspects of life. Individuals with this disorder often struggle with...
Anxiety: Overview01:18

Anxiety: Overview

Anxiety is a common mental disorder featuring excessive worry, fear, and apprehension, significantly affecting daily life. People with anxiety disorders experience persistent and intense anxiety, interrupting their everyday functioning.
Individuals with anxiety often experience a range of physical and emotional symptoms, including sweating, trembling, tachycardia, and disturbances in sleep patterns. These symptoms vary in intensity and frequency but are generally disruptive and distressing.
Introduction to Psychological Disorders01:19

Introduction to Psychological Disorders

Abnormal behavior, often referred to as mental illness, results from changes in brain function that influence thought patterns, behaviors, and social interactions. Psychologists and psychiatrists typically assess abnormal behavior using three primary criteria: deviance, maladaptation, and personal distress, particularly when these traits persist over long periods.
Deviant Behavior
Deviance in behavior refers to actions or thought patterns that significantly diverge from societal norms or...

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Regional, functional and transcriptomic decoding of multidimensional brain structure alterations in obsessive-compulsive disorder.

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Related Experiment Video

Updated: Jul 14, 2026

Exploring the Neural Correlates of Cognitive Reappraisal in Obsessive-Compulsive Disorder Using Task-based Functional Magnetic Resonance Imaging
09:14

Exploring the Neural Correlates of Cognitive Reappraisal in Obsessive-Compulsive Disorder Using Task-based Functional Magnetic Resonance Imaging

Published on: March 14, 2025

Symptom dimensions in obsessive-compulsive disorder: implications for the DSM-V.

James F Leckman1, Scott L Rauch, David Mataix-Cols

  • 1Child Study Center, Yale University School of Medicine, New Haven, CT 06520-7900, USA. james.leckman@yale.edu

CNS Spectrums
|May 22, 2007
PubMed
Summary

Obsessive-compulsive disorder (OCD) symptoms can be understood through stable dimensions, offering insights into its nature. This dimensional approach aids in identifying endophenotypes and improving understanding of OCD's genetics and neurobiology.

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Exploring the Neural Correlates of Cognitive Reappraisal in Obsessive-Compulsive Disorder Using Task-based Functional Magnetic Resonance Imaging
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Protocol for Repetitive Transcranial Magnetic Stimulation with Symptom Provocation to Treat Obsessive-compulsive Disorder
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Area of Science:

  • Psychiatry
  • Neuroscience
  • Genetics

Background:

  • Obsessive-compulsive disorder (OCD) lacks clear etiological markers and a unified pathophysiology.
  • The complex clinical presentation of OCD can be simplified through consistent symptom dimensions.

Purpose of the Study:

  • To explore the utility of obsessive-compulsive (OC) symptom dimensions as a framework for understanding OCD.
  • To investigate the potential of a dimensional approach in identifying robust endophenotypes for OCD research.

Main Methods:

  • Quantitative analysis of OC symptom dimensions.
  • Review of preliminary data on the application of dimensional phenotypes in OCD studies.

Main Results:

  • OC symptom dimensions provide a spectrum of features that may bridge normal worries and OCD.
  • Dimensional phenotypes show promise for advancing research in OCD's natural history, genetics, neurobiology, and treatment outcomes.
  • Age-of-onset and tic-related status are useful categorical distinctions within the dimensional framework.

Conclusions:

  • A dimensional approach to OC symptoms offers a valuable perspective for OCD research, complementing other methods.
  • Further development of dimensional assessment scales is necessary for clinical and population-based studies.