Related Experiment Video
Updated: Jul 14, 2026

12:04
Assessment of Bone Fracture Healing Using Micro-Computed Tomography
Published on: December 9, 2022
Computerized tomography evaluation of cortical bone properties in the tibia.
Marek Kowalczyk1, Andrzej Wall, Tomasz Turek
1Katedra i Klinika Ortopedii i Traumatologii Narzadu Ruchu Akademii Medycznej, Wrocław. marekkowalczyk1@gazeta.pl
Ortopedia, Traumatologia, Rehabilitacja
|May 22, 2007
Summary
Tibia bone density decreases with age, contrary to the hypothesis that bone loss is compensated by increased outer bone growth. This study examined CT scans of cadaver tibiae to assess bone density and cortical area.
Area of Science:
- Orthopedic research
- Bone densitometry
- Geriatric skeletal health
Background:
- Tibia shaft fractures are common, but their incidence doesn't rise in the elderly.
- Osteoporotic bone resorption may be offset by periosteal apposition, potentially improving bone mechanics.
- Investigating age-related changes in tibial bone structure is crucial for understanding fracture risk.
Purpose of the Study:
- To determine if geometric indices from transverse bone scans correlate with radiologic bone density.
- To explore the relationship between aging, bone resorption, and periosteal apposition in the tibia.
Main Methods:
- Computed tomography (CT) examination of 12 human cadaver tibiae.
- Evaluation of radiological bone density (Hounsfield units) in transverse scans.
- Measurement of average and maximum bone density and cortical bone area.
Main Results:
- Average radiological bone density showed a decrease with increasing age.
- The decrease in bone density was not associated with a compensatory increase in cortical bone area.
Conclusions:
- The study did not find direct evidence supporting periosteal apposition compensating for age-related osteoporotic bone resorption in the tibia.
- Findings suggest that other factors may be involved in maintaining tibial structural integrity in the elderly.
Related Concept Videos
Imaging Studies III: Computed Tomography
DefinitionComputed Tomography (CT) of the genitourinary (GU) tract is a non-invasive imaging modality that utilizes X-rays and computer processing to generate detailed cross-sectional images of the urinary system, encompassing the kidneys, ureters, bladder, and adjacent structures such as the adrenal glands.PurposeCT scans of the GU tract serve several diagnostic and therapeutic purposes, including:Diagnosis of Urinary Tract Diseases: Detects kidney stones, tumors, cysts, and congenital...
Bones of the Lower Limb: Tibia and Fibula
The tibia is the main weight-bearing bone of the lower leg. It is larger than the fibula with which it is paired. The tibia is also the second longest bone in the body and is located right below the skin. The proximal end of the tibia forms the medial and the lateral condyle, which articulates with the condyles of the femur to form the knee joint. Between the articulating surfaces is the irregular elevated area known as the intercondylar eminence that serves as the inferior attachment point for...
Computed Tomography
Tomography refers to imaging by sections. Computed tomography (CT) is a non-invasive imaging technique that uses computers to analyze several cross-sectional X-rays to reveal minute details about structures in the body.
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...

