Related Concept Videos
01:25Acute Pancreatitis I: Introduction
Acute pancreatitis is the sudden inflammation of the pancreas caused by the early activation of digestive enzymes, leading to the autodigestion of pancreatic tissue. This results in local inflammation and, in severe cases, systemic complications.EtiologyUnderstanding the underlying causes is crucial, as identifying the etiology guides treatment and anticipates complications. Acute pancreatitis can be triggered by various factors, typically grouped into the following clinical categories.Biliary...
01:27Acute Pancreatitis I: Introduction
Pancreatitis is inflammation of the pancreas, an organ located behind the stomach. It can be either acute or chronic.
Acute pancreatitis is characterized by rapid inflammation of the pancreas, often caused by factors like gallstone blockage or excessive alcohol consumption. Chronic pancreatitis, on the other hand, is a slow, progressive inflammation that may result from long-term alcohol abuse, obstructions in the pancreatic duct, or genetic factors.
The causes of acute pancreatitis include:
Acute pancreatitis is characterized by rapid inflammation of the pancreas, often caused by factors like gallstone blockage or excessive alcohol consumption. Chronic pancreatitis, on the other hand, is a slow, progressive inflammation that may result from long-term alcohol abuse, obstructions in the pancreatic duct, or genetic factors.
The causes of acute pancreatitis include:
01:30Acute Pancreatitis II: Clinical Manifestations and Management
Acute pancreatitis presents a complex medical emergency characterized by rapid onset inflammation of the pancreas, demanding timely diagnosis and management to prevent complications. The condition primarily manifests through severe upper abdominal pain that often radiates to the back. This pain intensifies following the consumption of fatty foods. Accompanying symptoms such as nausea, vomiting, abdominal distention, fever, dyspnea, cyanosis, and jaundice can vary in intensity but significantly...
01:21Acute Pancreatitis II: Pathophysiology
The pathophysiology of acute pancreatitis centers on injury to pancreatic acinar cells, which initiates a cascade of harmful intracellular events.This injury leads to premature activation of trypsinogen to trypsin in the pancreas. Trypsin then activates other digestive enzymes, such as chymotrypsin, elastase, and phospholipase A2, which begin breaking down pancreatic tissue. The resulting autodigestion causes local inflammation, tissue swelling, hemorrhage, and fat necrosis.Injured acinar cells...
01:29Chronic Pancreatitis II: Collaborative Care
The management of chronic pancreatitis is multifaceted, involving a comprehensive approach that includes thorough assessment, diagnostic testing, and a variety of management strategies.
Assessment:
Assessment:
01:25Ultrasound II: Endoscopic Ultrasound and FibroScan
Endoscopic Ultrasound (EUS) and FibroScan are valuable diagnostic tools in gastroenterology and hepatology, each with specific applications and techniques.
Endoscopic Ultrasound (EUS):
Endoscopic Ultrasound (EUS):
You might also read
Related Articles
Articles linked to this work by shared authors, journal, and citation graph.
Sort by
Same author
A case series is not enough to properly study potential adverse events of the endoscopic over-the-scope clips and cutters.
Gastrointestinal endoscopy·2025
Same author
Correction: Pilot evaluation of a novel, automated ergonomics assessment tool.
Endoscopy international open·2025
Acute severe pancreatitis: contrast-enhanced sonography.
Steffen Rickes1, Klaus Mönkemüller, Peter Malfertheiner
1Department of Gastroenterology, Hepatology and Infectious Diseases Otto-von-Guericke-University, Leipziger Str. 44, 39120, Magdeburg, Germany. steffen.rickes@medizin.uni-magdeburg.de
Abdominal Imaging
|May 22, 2007
Summary
Contrast-enhanced ultrasound effectively detects pancreatic necrosis in severe acute pancreatitis. This imaging technique improves upon conventional ultrasound by assessing organ perfusion, aiding in early differentiation of pancreatitis types.
Area of Science:
- Medical Imaging
- Gastroenterology
- Pancreatology
Background:
- Early differentiation between oedematous and necrotizing acute pancreatitis is crucial for guiding treatment.
- Conventional transabdominal ultrasound has limitations in detecting pancreatic necrosis due to its inability to assess organ perfusion.
- Spiral computed tomography is the current gold standard for staging severe acute pancreatitis.
Purpose of the Study:
- To evaluate the utility of contrast-enhanced ultrasound (CEUS) for detecting parenchymal necrosis in acute severe pancreatitis.
- To highlight the advancements in ultrasound technology for assessing pancreatic vascularization.
- To provide an update on the role of CEUS in managing acute severe pancreatitis.
Main Methods:
- Review of current literature on ultrasound techniques in acute pancreatitis.
- Focus on the principles and application of contrast-enhanced ultrasound.
- Discussion of CEUS's ability to visualize pancreatic and liver parenchyma perfusion.
Main Results:
- Contrast-enhancement allows ultrasound to assess organ perfusion, overcoming limitations of conventional methods.
- CEUS can provide detailed examination of vascularization behaviour in the pancreas and liver.
- This technique facilitates the detection of parenchymal necrosis, previously difficult with standard ultrasound.
Conclusions:
- Contrast-enhanced ultrasound is a valuable tool for detecting parenchymal necrosis in acute severe pancreatitis.
- CEUS offers a viable alternative or adjunct to CT for assessing pancreatic perfusion and necrosis.
- Improved imaging of vascularization aids in the early and accurate staging of acute pancreatitis.