Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Obesity01:24

Obesity

The Body Mass Index (BMI) is a numerical value derived from a person's weight and height, used to categorize individuals into weight ranges. It is calculated using the formula: weight in kilograms divided by height in meters squared. Obesity is a health condition characterized by excessive accumulation of adipose tissue that poses health risks, often diagnosed with a BMI ≥ 30. This excess fat storage occurs when surplus dietary calories are converted into triglycerides and stored in adipocytes...
Drug Dosing: Obese Patients01:21

Drug Dosing: Obese Patients

In the United States, obesity is a prominent concern. It is linked to heightened mortality rates due to increased occurrences of conditions such as hypertension, atherosclerosis, coronary artery disease, and diabetes compared to nonobese individuals. A patient is classified as obese if their actual body weight surpasses the ideal or desirable body weight by 20%, based on Metropolitan Life Insurance Company data. Ideal body weights consider average weights and heights for males and females...
Binge Eating Disorders01:23

Binge Eating Disorders

Binge eating disorder is a significant mental health condition characterized by recurrent episodes of excessive food consumption within a short period, accompanied by a perceived loss of control over eating behavior. Unlike occasional overeating, binge eating disorder is marked by distressing emotions such as guilt, shame, and anxiety following binge episodes. The disorder affects individuals across different ages and backgrounds, with profound implications for physical and psychological...
Pharmacokinetics in Obese Patients: Drug Absorption and Distribution01:25

Pharmacokinetics in Obese Patients: Drug Absorption and Distribution

Obesity significantly alters the pharmacokinetic processes of drug absorption and distribution, presenting unique challenges in medical treatment. The increased fat tissue and decreased lean muscle in obese individuals can significantly affect how drugs are absorbed into the body and distributed across different tissues. This alteration can lead to variances in the effectiveness and safety of medications, necessitating adjustments in dosing or drug selection for obese patients.One notable...
Pharmacokinetics in Obese Patients: Drug Metabolism and Excretion01:20

Pharmacokinetics in Obese Patients: Drug Metabolism and Excretion

Drug metabolism, a critical process in the liver, involves two primary phases: Phase I reactions and Phase II conjugation. Obesity introduces significant alterations in this metabolic process, primarily due to fatty infiltration of the liver, leading to conditions such as nonalcoholic fatty liver disease (NAFLD). This condition can modify the activities of both Phase I and II enzymes, impacting how drugs are metabolized in obese patients.Phase I metabolism sees variable effects across...
Regulation of Food Intake01:30

Regulation of Food Intake

Short-term regulation of food intake primarily involves neural signals from the gastrointestinal (GI) tract, blood nutrient levels, and GI tract hormones. Communication between the gut and brain via vagal nerve fibers plays a significant role in evaluating the contents of the gut. Clinical studies have shown that protein ingestion produces a more prolonged response in these nerve fibers compared to an equivalent amount of glucose. Additionally, the activation of stretch receptors caused by GI...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Characterizing Particulate Matter Impacts of Smoke From 2022 to 2023 Agricultural Burning in South Florida.

GeoHealth·2026
Same author

Association of Regional Agricultural Smoke Exposure With Sociodemographic Factors in Rural and Urban Communities.

GeoHealth·2026
Same author

Public Health.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2025
Same author

Public Health.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2025
Same author

Public Health.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2025
Same author

Evidence-based facilitator strategies for enhancing social engagement in groups of older adults with ADRD.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2025

Related Experiment Video

Updated: Jul 14, 2026

Control of Eating Behavior Using a Novel Feedback System
04:48

Control of Eating Behavior Using a Novel Feedback System

Published on: May 8, 2018

Weight control among obese adolescents: a pilot study.

Christine L Williams1, Barbara A Strobino, Jane Brotanek

  • 1Department of Pediatrics, Section of Gastroenterology, Hepatology and Nutrition, Columbia University, College of Physicians and Surgeons, Morgan Stanley Children's Hospital of NY - Presbyterian, 3959 Broadway, New York, NY 10032, USA. chrisw320@aol.com

International Journal of Food Sciences and Nutrition
|May 22, 2007
PubMed
Summary

A 12-week weight loss program for overweight teen girls showed that allowing a 150-calorie free snack was as effective as a restricted snack policy. Both diets achieved modest weight loss and were well-accepted.

More Related Videos

Multidisciplinary Approach to Obesity Management: A Case Report
05:10

Multidisciplinary Approach to Obesity Management: A Case Report

Published on: May 30, 2025

Influence of Emotional Factors on the Efficacy of Acupuncture Treatment for Overweight Complicated with Hyperlipidemia: A Retrospective Cohort Study
03:05

Influence of Emotional Factors on the Efficacy of Acupuncture Treatment for Overweight Complicated with Hyperlipidemia: A Retrospective Cohort Study

Published on: November 21, 2025

Related Experiment Videos

Last Updated: Jul 14, 2026

Control of Eating Behavior Using a Novel Feedback System
04:48

Control of Eating Behavior Using a Novel Feedback System

Published on: May 8, 2018

Multidisciplinary Approach to Obesity Management: A Case Report
05:10

Multidisciplinary Approach to Obesity Management: A Case Report

Published on: May 30, 2025

Influence of Emotional Factors on the Efficacy of Acupuncture Treatment for Overweight Complicated with Hyperlipidemia: A Retrospective Cohort Study
03:05

Influence of Emotional Factors on the Efficacy of Acupuncture Treatment for Overweight Complicated with Hyperlipidemia: A Retrospective Cohort Study

Published on: November 21, 2025

Area of Science:

  • Pediatric Endocrinology
  • Nutritional Science
  • Clinical Trials

Background:

  • Overweight adolescents (BMI ≥ 95th percentile) require effective weight management strategies.
  • Dietary interventions for adolescent weight loss need to consider compliance and snack choices.
  • Calcium intake is crucial for bone health in adolescents, and supplementation may be necessary.

Purpose of the Study:

  • To compare weight loss and compliance in overweight adolescent girls using two different 1,500 kcal/day dietary interventions.
  • To evaluate the impact of snack flexibility (free vs. restricted) on weight management outcomes.
  • To assess the role of dairy consumption and calcium supplementation in adolescent weight control.

Main Methods:

  • A 12-week controlled clinical trial involving overweight adolescent girls aged 11-15 years.
  • Random assignment to either a 1,500 kcal/day free-snack (150 kcal/snack) or restricted-snack (diet soda only) program.
  • All participants received counseling for 3 daily servings of dairy and a 500 mg calcium supplement.

Main Results:

  • Thirty-two girls completed the study; both diets yielded similar modest weight loss.
  • Both dietary approaches were equally acceptable to participants.
  • Significant reductions were observed in weight, BMI, anthropometric measures, total cholesterol, and triglycerides.

Conclusions:

  • A 1,500 kcal/day diet with a 150-calorie free snack option is as effective for weight loss as a more restricted snack policy in overweight adolescent girls.
  • Incorporating some soda into teen weight control diets is feasible if caloric intake is managed and nutrient needs are met.
  • While calcium supplementation improved intake, further emphasis on calcium-rich foods is needed for optimal adolescent nutrition.