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Related Experiment Video

Updated: Jul 14, 2026

Normothermic Ex Vivo Kidney Perfusion for the Preservation of Kidney Grafts prior to Transplantation

Normothermic Ex Vivo Kidney Perfusion for the Preservation of Kidney Grafts prior to Transplantation

Published on: July 15, 2015

Paired exchange programmes can expand the live kidney donor pool.

A O Mahendran¹, P S Veitch

¹Renal Transplantation Unit, Royal Free Hospital and University College London Medical School, Pond Street, London NW3 2QG, UK.

The British Journal of Surgery

|May 22, 2007

Summary

Kidney paired donation (KPD) facilitates transplants between incompatible donor-recipient pairs, increasing organ availability. Addressing ethical and logistical challenges is key to expanding this life-saving strategy.

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Heterotopic Renal Autotransplantation in a Porcine Model: A Step-by-Step Protocol

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Area of Science:

Nephrology
Transplantation immunology
Organ donation policy

Background:

Kidney paired donation (KPD) involves exchanging organs between incompatible live donor-recipient pairs.
KPD aims to improve recipient quality of life and longevity through compatible transplants.

Purpose of the Study:

To review the literature on kidney paired donation (KPD).
To identify protocols, policies, and barriers associated with KPD programs.

Main Methods:

Systematic literature search of Medline using relevant keywords.
Identification and analysis of publications on KPD protocols, policy, modeling, ethics, and logistics.

Main Results:

KPD increases transplantation rates for incompatible donor-recipient pairs.
Ethical issues include confidentiality, conditionality, synchronicity, and potential disadvantage to blood group O recipients.
Logistical barriers involve donor surgery location and organ transport.

Conclusions:

KPD expands the living donor pool, offering a viable strategy for incompatible pairs.
Widespread KPD implementation requires resolution of ethical and logistical constraints.