Reliability of serial bone scintigraphy classification according to Conway in Legg-Calvé-Perthes disease

Anja Van Campenhout1, Pierre Moens, Guy Fabry

  • 1Department of Orthopaedics, University Hospitals Leuven, Pellenberg, Belgium. anja.vancampenhout@uz.kuleuven.ac.be

Insights

Serial bone scintigraphy for Legg-Calvé-Perthes disease (LCP) shows moderate reliability. This early prognostic tool

Area of Science:

  • Pediatric Orthopedics
  • Nuclear Medicine
  • Skeletal Imaging

Background:

  • Legg-Calvé-Perthes disease (LCP) is a hip disorder affecting children.
  • Serial bone scintigraphy is utilized for early prognosis in LCP.
  • No prior studies have assessed the reliability of scintigraphic classifications for LCP.

Purpose of the Study:

  • To evaluate the intra- and inter-observer reliability of the Conway classification for serial bone scintigraphy in Legg-Calvé-Perthes disease.
  • To compare the reliability of scintigraphic classification with established radiological methods.

Main Methods:

  • Forty pediatric hips diagnosed with LCP disease underwent serial technetium scintigraphy.
  • Six observers independently classified the scintigraphic patterns twice, with a minimum one-month interval.
  • Unweighted kappa coefficients were calculated to determine reliability.

Main Results:

  • Moderate intra-observer reliability was found (kappa = 0.573).
  • Moderate inter-observer reliability was observed (kappa = 0.525).
  • Scintigraphic reliability was superior to Catterall classification and head-at-risk factors but inferior to Herring classification.

Conclusions:

  • Serial bone scintigraphy for LCP demonstrates only moderate intra- and inter-observer reliability.
  • While useful for early prognosis, the Conway classification's reliability necessitates careful consideration.
  • Further refinement of scintigraphic assessment criteria may be warranted to improve diagnostic consistency.