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Utility of coronary MR angiography in children with Kawasaki disease
Atsushi Takemura1, Atsuko Suzuki, Rikako Inaba
1Department of Radiology, Tokyo Postal Services Agency Hospital, Chiyoda-ku, Fujimi 2-chome, 14-23, Tokyo, Japan 102-8798. atsu-papa@mm.em-net.ne.jp
Insights
Optimized magnetic resonance (MR) coronary angiography provides high-quality images for evaluating coronary artery issues in children with Kawasaki disease (KD). This noninvasive technique improves image clarity and detection rates, even for infants.
Area of Science:
- Cardiovascular Imaging
- Pediatric Cardiology
- Medical Diagnostics
Background:
- Coronary arterial lesions in Kawasaki disease (KD) require early evaluation.
- Conventional X-ray coronary angiography poses significant risks for young children.
- Noninvasive MR coronary angiography is desirable but challenging in pediatric populations.
Purpose of the Study:
- To develop and optimize a method for high-quality MR coronary angiography in young children with KD.
- To improve the diagnostic accuracy of noninvasive coronary imaging in pediatric KD patients.
Main Methods:
- Utilized MR coronary angiography with vector electrocardiogram gating, real-time navigator-echo, 3D steady-state free precession.
- Performed the technique on 35 children diagnosed with Kawasaki disease.
- Optimized key imaging parameters including field of view, acquisition delay, turbo-field echo-factor, navigator window, and resolution for each patient.
Main Results:
- Achieved high-resolution and high-signal-to-noise ratio images of coronary arteries.
- Significantly enhanced image quality compared to previous methods.
- Improved the detection rate of coronary artery segments, aiding in lesion identification.
Conclusions:
- Optimized MR coronary angiography is a valuable tool for early detection of coronary aneurysms in Kawasaki disease.
- The noninvasive method is effective even in infants and small children, offering a safer alternative to conventional angiography.
- This technique enhances diagnostic capabilities for pediatric cardiovascular conditions like KD.
Objective:
Although coronary arterial lesions due to Kawasaki disease (KD) should be evaluated as early as possible after the acute phase, conventional X-ray coronary angiography poses high risks for young children with the disease. The use of noninvasive MR coronary angiography is desirable, although it is difficult to produce clear images in young children. We developed a method to improve the quality of MR coronary angiography in young children. MR coronary angiography with vector electrocardiogram gating, real-time navigator-echo, 3D, steady-state free precession was performed in 35 children with KD. Many parameters (i.e., field of view, acquisition delay, turbo-field echo-factor, navigator window, and resolution) were optimized for each patient.
Conclusion:
Optimization resulted in the acquisition of high-resolution and highsignal images of the coronary arteries. It remarkably improved not only the quality of the images, but also the detection rate of coronary artery segments. MR coronary angiography is a useful method for evaluating coronary aneurysms from the early stages of KD, even in infants and small children.
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