[Iotrolan-300 versus Iopamidol-300 in hysterosalpingography]

From 9.1988 to 7.1989 we carried out on 50 patients at the Department of Gynaecology of the University of Freiburg a randomized double-blind study to compare the first dimeric, nonionic, hexaiodinated, water-soluble contrast agent (Iotrolan-300 corresponding to Isovist-300) with a nonionic, monomeric preparation (Iopamidol-300 corresponding to Solutrast-300) using the concentration of 300 mg I/ml. Both medicaments show a high contrast quality in the X-rays. Complications like hypersensitivity reactions resp. actual local irritations were not recorded. Iotrolan-300 was found to be the best tolerated of the two contrast media in respect of mildest intensity of pain.