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Related Experiment Video

Updated: Jul 14, 2026

The Pocket-Creation Procedure of Endoscopic Submucosal Dissection for Large Rectal Laterally Spreading Tumors
04:09

The Pocket-Creation Procedure of Endoscopic Submucosal Dissection for Large Rectal Laterally Spreading Tumors

Published on: February 13, 2026

Endoscopic submucosal dissection: a safe technique for colorectal tumors.

Y Tamegai1, Y Saito, N Masaki

  • 1Department of Gastroenterology, International Medical Center of Japan, Tokyo, Japan. ytamegai@imcj.hosp.go.jp

Endoscopy
|May 23, 2007
PubMed
Summary

Endoscopic submucosal dissection (ESD) offers a safe and effective method for removing large colorectal tumors, achieving a high en bloc resection rate. This technique shows lower recurrence rates compared to conventional endoscopic mucosal resection (EMR).

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Area of Science:

  • Gastroenterology
  • Endoscopic Surgery
  • Oncology

Background:

  • Endoscopic submucosal dissection (ESD) enables en bloc resection of large neoplastic lesions for precise histopathological analysis.
  • Colorectal tumors pose a challenge for complete endoscopic removal.

Purpose of the Study:

  • To analyze the technical and clinical outcomes of endoscopic submucosal dissection (ESD) for colorectal tumors.
  • To compare ESD outcomes with conventional piecemeal endoscopic mucosal resection (EMR).

Main Methods:

  • Retrospective analysis of 71 colorectal neoplasms treated with ESD in 70 patients.
  • Evaluation of lesion size, procedure time, complications, and outcomes.
  • Comparison with 32 lesions treated by piecemeal EMR.

Related Experiment Videos

Last Updated: Jul 14, 2026

The Pocket-Creation Procedure of Endoscopic Submucosal Dissection for Large Rectal Laterally Spreading Tumors
04:09

The Pocket-Creation Procedure of Endoscopic Submucosal Dissection for Large Rectal Laterally Spreading Tumors

Published on: February 13, 2026

Main Results:

  • ESD achieved an en bloc resection rate of 98.6% for large colorectal neoplasms (average size 32.7 mm).
  • The ESD group had no recurrence after a mean follow-up of 12.2 months, versus 6.3% recurrence in the EMR group.
  • Complications were minimal, with one perforation (1.4%) managed conservatively.

Conclusions:

  • Endoscopic submucosal dissection (ESD) is a safe and effective technique for large colorectal neoplasms.
  • ESD demonstrates superior outcomes to piecemeal EMR, with potential to replace it in most cases.