Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Epithelioid cell clusters with an extensive lymphoid background.

Matthew A Zarka1

  • 1Department of Laboratory Medicine and Pathology, Mayo Clinic Arizona, 13400 E Shea Blvd, Scottsdale, AZ 85259, USA. zarka.matthew@mayo.edu

Archives of Pathology & Laboratory Medicine
|May 23, 2007
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Pulmonary Artery Angiomatoid Fibrous Histiocytoma Mimicking a Large Pulmonary Embolism.

Clinical nuclear medicine·2022
Same author

Cytomorphology of NUTM1-rearranged sarcoma involving pleural fluid.

Diagnostic cytopathology·2022
Same author

Improving Oncology-Pathology Collaboration in Resource-Limited Settings: An American Society of Clinical Oncology/College of American Pathologists Initiative.

American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting·2021
Same author

Transcriptomic and Immunophenotypic Characterization of Tumor Immune Microenvironment in Squamous Cell Carcinoma of the Oral Tongue.

Head and neck pathology·2020
Same author

Cytologic grading of primary malignant salivary gland tumors: A blinded review by an international panel.

Cancer cytopathology·2020
Same author

Histopathological characteristics of surgical tissue from primary vs recurrent chronic rhinosinusitis with nasal polyposis patients.

Laryngoscope investigative otolaryngology·2020
Same journal

Centenary of Archives of Pathology & Laboratory Medicine: Its Conception, Gestation, Birth, Childhood, and Maturation.

Archives of pathology & laboratory medicine·2026
Same journal

Assessing Human Epidermal Growth Factor Receptor 2 in Urothelial Carcinoma: Insights From Clinical Practice Into Scoring Criteria, Histologic Subtypes, and Genomic Characteristics Across Disease Sites.

Archives of pathology & laboratory medicine·2026
Same journal

Cross-Reactivity of TPIT Antibody Clone OTI2G1 in Chordoma: Structural Mechanisms and Diagnostic Implications.

Archives of pathology & laboratory medicine·2026
Same journal

Paracoccidioidomycosis at Autopsy: A Case Series and Literature Review.

Archives of pathology & laboratory medicine·2026
Same journal

Accuracy of Cytology Diagnosis for Well Differentiated Neuroendocrine Tumors: Assessment by the College of American Pathologists Non-Gynecologic Slide Program.

Archives of pathology & laboratory medicine·2026
Same journal

Serum Immunofixation Electrophoresis Guidance Conflict: A Call to Harmonize.

Archives of pathology & laboratory medicine·2026
See all related articles

Diagnosing salivary gland lesions via fine-needle aspiration is complex. A pattern recognition approach, focusing on architectural patterns and unique cellular features, aids pathologists in accurate diagnosis.

Area of Science:

  • Cytopathology
  • Surgical Pathology
  • Head and Neck Oncology

Background:

  • Fine-needle aspiration (FNA) of salivary gland lesions presents diagnostic challenges due to numerous neoplasms and cytologic variations.
  • Accurate diagnosis is crucial for appropriate patient management and treatment planning.

Purpose of the Study:

  • To introduce a practical pattern recognition strategy for salivary gland FNA diagnosis.
  • To categorize lesions based on shared cytologic architectural patterns and unique cellular features.
  • To discuss the common pattern of 'epithelioid cell clusters with an extensive lymphoid background' in salivary gland cytopathology.

Main Methods:

  • Review of published literature.
  • Analysis of personal diagnostic experience.

Related Experiment Videos

Main Results:

  • A pattern recognition approach, categorizing lesions by architectural patterns and specific cellular details, can improve diagnostic accuracy.
  • The pattern 'epithelioid cell clusters with an extensive lymphoid background' is frequently observed.
  • This pattern encompasses various benign and malignant entities, including Warthin tumor.

Conclusions:

  • A cytologic architectural pattern-based method is valuable for diagnosing salivary gland lesions.
  • Distinguishing between entities within the 'epithelioid cell clusters with an extensive lymphoid background' pattern relies on identifying unique cytologic features.
  • This systematic approach assists pathologists in achieving correct diagnoses for salivary gland neoplasms.