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Updated: Jul 14, 2026

Extrahepatic Bile Duct and Gall Bladder Dissection in Nine-Day-Old Mouse Neonates
Published on: August 23, 2022
Agenesis of the gallbladder.
Oreste Nardello1, Marilena Muggianu, Marino Cagetti
1Università degli Studi di Cagliari, Dipartimento Chirurgico Materno-Infantile e Scienze delle Immagini, Clinica Chirurgica, Italy. orenar@tiscali.it
Gallbladder agenesis is rare and often asymptomatic, but can mimic biliary disorders. Diagnosis is challenging, especially with associated dysplastic cysts, often requiring surgery for confirmation and treatment.
Area of Science:
- Gastroenterology and Hepatobiliary Surgery
- Congenital Anomalies
- Diagnostic Imaging
Background:
- Gallbladder agenesis is a rare congenital anomaly with variable clinical presentations.
- Preoperative diagnosis can be challenging, particularly when associated with other biliary tract abnormalities.
- Symptoms may mimic common biliary disorders such as cholelithiasis.
Observation:
- This case highlights the diagnostic difficulties of gallbladder agenesis when a dysplastic cyst is present.
- The dysplastic cyst can simulate the gallbladder, complicating preoperative assessment.
- Surgical intervention is often necessary for definitive diagnosis and management.
Findings:
- Gallbladder agenesis associated with a dysplastic cyst presents a unique diagnostic challenge.
- Open surgery, careful common bile duct dissection, and intraoperative imaging are crucial for confirmation.
- Associated anomalies must be excluded during surgical exploration.
Implications:
- Accurate diagnosis and management of gallbladder agenesis are essential to prevent complications.
- Surgical planning must account for potential associated anomalies and the need for precise dissection.
- This case underscores the importance of advanced imaging and surgical techniques in managing rare biliary tract anomalies.
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