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Generalized vasculitic exanthem following Loxosceles reclusa envenomation
Christopher W Robb1, Benjamin B Hayes, Alan S Boyd
1Division of Dermatology, Department of Internal Medicine, Vanderbilt University, Nashville, TN 37232, USA.
Abstract:
Brown recluse spider bites (BRSB) cause a myriad of reactions ranging from local necrosis to potentially lethal systemic involvement. Envenomation may induce a generalized exanthem known clinically but not described histologically. We report a 49-year-old female who developed a generalized exanthem 24 hours after BRSB. The histopathology demonstrated a necrotizing vasculitis similar to that seen at an envenomation site but without epidermal necrosis. Loxoscelism should be considered in patients residing in endemic areas who present with a vasculitic exanthem.
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